Mechanism of Action, Resistance, Synergism, and Clinical Implications of Delamanid Against Multidrug-Resistant Mycobacterium tuberculosis
Multidrug-resistant (MDR) isolates of Mycobacterium tuberculosis (MTB) remain a primary
global threat to the end of tuberculosis (TB) era. Delamanid (DLM) is a nitro-dihydro …
global threat to the end of tuberculosis (TB) era. Delamanid (DLM) is a nitro-dihydro …
[HTML][HTML] Delamanid-containing regimens and multidrug-resistant tuberculosis: A systematic review and meta-analysis
Introduction Multidrug-resistant tuberculosis (MDR-TB) is a life-threatening condition
needing long poly-chemotherapy regimens. As no systematic reviews/meta-analysis is …
needing long poly-chemotherapy regimens. As no systematic reviews/meta-analysis is …
Culture conversion in patients treated with bedaquiline and/or delamanid. A prospective multicountry study
Rationale: Bedaquiline and delamanid offer the possibility of more effective and less toxic
treatment for multidrug-resistant (MDR) tuberculosis (TB). With this treatment, however …
treatment for multidrug-resistant (MDR) tuberculosis (TB). With this treatment, however …
[HTML][HTML] Global treatment outcomes of extensively drug-resistant tuberculosis in adults: A systematic review and meta-analysis
OS Pedersen, FB Holmgaard, MKD Mikkelsen… - Journal of Infection, 2023 - Elsevier
Introduction Historically, extensively drug-resistant tuberculosis has been notoriously difficult
to treat with devasting outcomes. As we are coming to the end of an era where the 2006 …
to treat with devasting outcomes. As we are coming to the end of an era where the 2006 …
[HTML][HTML] Diagnosis and treatment of multidrug-resistant tuberculosis
JG Jang, JH Chung - Yeungnam University journal of …, 2020 - synapse.koreamed.org
Tuberculosis (TB) is still a major health problem worldwide. Especially, multidrug-resistant
TB (MDR-TB), which is defined as TB that shows resistance to both isoniazid and rifampicin …
TB (MDR-TB), which is defined as TB that shows resistance to both isoniazid and rifampicin …
Unraveling Dilemmas and Lacunae in the Escalating Drug Resistance of Mycobacterium tuberculosis to Bedaquiline, Delamanid, and Pretomanid
Delamanid, bedaquiline, and pretomanid have been recently added in the anti-tuberculosis
(anti-TB) treatment regimens and have emerged as potential solutions for combating drug …
(anti-TB) treatment regimens and have emerged as potential solutions for combating drug …
[HTML][HTML] Interim treatment outcomes in multidrug-resistant tuberculosis using bedaquiline and/or delamanid in South Korea
Abstract Purpose The Korea Centers for Disease Control & Prevention has implemented a
review process for the approval of new drugs used to treat patients with multidrug-resistant …
review process for the approval of new drugs used to treat patients with multidrug-resistant …
Impact of Prior Tuberculosis Treatment With New/Companion Drugs on Clinical Outcomes in Patients Receiving Concomitant Bedaquiline and Delamanid for …
L Mikiashvili, RR Kempker, TS Chakhaia… - Clinical Infectious …, 2024 - academic.oup.com
Background There are scarce data on the clinical outcomes of persons retreated with
new/companion anti-tuberculosis (TB) drugs for multidrug-and rifampicin-resistant …
new/companion anti-tuberculosis (TB) drugs for multidrug-and rifampicin-resistant …
Outcomes of multidrug-resistant tuberculosis treated with bedaquiline or delamanid
H Hwang, H Kang, YS Kwon, D Jeon… - Clinical Infectious …, 2021 - academic.oup.com
Abstract Background Since 1 September 2016, bedaquiline and delamanid have been
administered for the treatment of patients with multidrug-resistant/rifampicin-resistant …
administered for the treatment of patients with multidrug-resistant/rifampicin-resistant …
Treatment outcomes of patients with multidrug and extensively drug-resistant tuberculosis in Zhejiang, China
MW Zhang, L Zhou, Y Zhang, B Chen, Y Peng… - European journal of …, 2021 - Springer
Background The aim of this study was to assess the treatment outcomes of multidrug and
extensively drug-resistant tuberculosis (M/XDR-TB) in Zhejiang, China and to evaluate …
extensively drug-resistant tuberculosis (M/XDR-TB) in Zhejiang, China and to evaluate …