The concept of an epigenetic landscape describing potential cellular fates arising from
pluripotent cells, first advanced by Conrad Waddington, has evolved in light of experiments …

Collective cancer invasion with leader–follower organization is increasingly recognized as a
predominant mechanism in the metastatic cascade. Leader cells support cancer invasion by …

Beautiful images of animal cells cultured on surfaces are ubiquitous in biological research,
but these shapes also carry valuable information about the cells and the organism that they …

Mathematical and computational models can assist in gaining an understanding of cell
behavior at many levels of organization. Here, we review models in the literature that focus …

In recent years, the mathematical and computational sciences have developed novel
methodologies and insights that can aid in designing advanced bioreactors, microfluidic …

Migrating cells need to coordinate distinct leading and trailing edge dynamics but the
underlying mechanisms are unclear. Here, we combine experiments and mathematical …

Bursting is one of the fundamental rhythms that excitable cells can generate either in
response to incoming stimuli or intrinsically. It has been a topic of intense research in …

Interacting particle system (IPS) models have proven to be highly successful for describing
the spatial movement of organisms. However, it is challenging to infer the interaction rules …

Objective Chitosan (CS) and polycaprolactone (PCL) were added into a nerve scaffold of
poly (L‐lactide acid)(PLLA)/polypyrrole (PP y)‐based fibre films to solve the unmatch with …

Some dividing cells sense their shape by becoming polarized along their long axis. Cell
polarity is controlled in part by polarity proteins, like Rho GTPases, cycling between active …