Emerging platforms for high-throughput enzymatic bioassays
Enzymes have essential roles in catalyzing biological reactions and maintaining metabolic
systems. Many in vitro enzymatic bioassays have been developed for use in industrial and …
systems. Many in vitro enzymatic bioassays have been developed for use in industrial and …
A fully automated and integrated microfluidic system for efficient CTC detection and its application in hepatocellular carcinoma screening and prognosis
J Wang, Y Li, R Wang, C Han, S Xu, T You… - … Applied Materials & …, 2021 - ACS Publications
Analysis of circulating tumor cells (CTCs) is regarded as a useful diagnostic index to monitor
tumor development and guide precision medicine. Although the immunoassay is a common …
tumor development and guide precision medicine. Although the immunoassay is a common …
Functional analysis of single enzymes combining programmable molecular circuits with droplet-based microfluidics
The analysis of proteins at the single-molecule level reveals heterogeneous behaviours that
are masked in ensemble-averaged techniques. The digital quantification of enzymes …
are masked in ensemble-averaged techniques. The digital quantification of enzymes …
Facile and scalable tubing-free sample loading for droplet microfluidics
Droplet microfluidics has in recent years found a wide range of analytical and bioanalytical
applications. In droplet microfluidics, the samples that are discretized into droplets within the …
applications. In droplet microfluidics, the samples that are discretized into droplets within the …
Multiplex digital microRNA detection using cross-inhibitory DNA circuits
Y Rondelez, G Gines - ACS sensors, 2020 - ACS Publications
Ubiquitous post-transcriptional regulators in eukaryotes, microRNAs are currently emerging
as promising biomarkers of physiological and pathological processes. Multiplex and digital …
as promising biomarkers of physiological and pathological processes. Multiplex and digital …
Digital PCR system development accelerator—A methodology to emulate dPCR results
H Zhang, Z Yan, X Wang, M Gaňová… - Sensors and Actuators B …, 2022 - Elsevier
The development of a digital polymerase chain reaction (dPCR) system typically begins with
an idea for the system configuration and chip layout, followed by design, fabrication, and …
an idea for the system configuration and chip layout, followed by design, fabrication, and …
Silicon chambers for enhanced incubation and imaging of microfluidic droplets
Droplet microfluidics has become a powerful tool in life sciences, underlying digital assays,
single-cell sequencing or directed evolution, and it is making foray in physical sciences as …
single-cell sequencing or directed evolution, and it is making foray in physical sciences as …
[HTML][HTML] Automated and miniaturized screening of antibiotic combinations via robotic-printed combinatorial droplet platform
Antimicrobial resistance (AMR) has become a global health crisis in need of novel solutions.
To this end, antibiotic combination therapies, which combine multiple antibiotics for …
To this end, antibiotic combination therapies, which combine multiple antibiotics for …
Modular Droplet‐Based Fluidics for Large Volume Libraries of Individual Multiparametric Codes in Lab‐On‐Chip Systems
Droplet‐based lab‐on‐a‐chip systems offer vast possibilities in the manipulation, guidance,
tracking, and labeling of individual droplet‐based bioreactors. One of the targeted …
tracking, and labeling of individual droplet‐based bioreactors. One of the targeted …
Silicon as a microfluidic material for imaging and incubation of droplets
Droplet microfluidics has become a powerful tool in life sciences, underlying digital assays,
single-cell sequencing or directed evolution, and it is making foray in physical sciences as …
single-cell sequencing or directed evolution, and it is making foray in physical sciences as …