Soil viral diversity, ecology and climate change

JK Jansson, R Wu - Nature Reviews Microbiology, 2023 - nature.com
Soil viruses are highly abundant and have important roles in the regulation of host dynamics
and soil ecology. Climate change is resulting in unprecedented changes to soil ecosystems …

Giant virus biology and diversity in the era of genome-resolved metagenomics

F Schulz, C Abergel, T Woyke - Nature Reviews Microbiology, 2022 - nature.com
The discovery of giant viruses, with capsids as large as some bacteria, megabase-range
genomes and a variety of traits typically found only in cellular organisms, was one of the …

Identification of mobile genetic elements with geNomad

AP Camargo, S Roux, F Schulz, M Babinski, Y Xu… - Nature …, 2024 - nature.com
Identifying and characterizing mobile genetic elements in sequencing data is essential for
understanding their diversity, ecology, biotechnological applications and impact on public …

Introducing the bacterial and viral bioinformatics resource center (BV-BRC): a resource combining PATRIC, IRD and ViPR

RD Olson, R Assaf, T Brettin, N Conrad… - Nucleic acids …, 2023 - academic.oup.com
Abstract The National Institute of Allergy and Infectious Diseases (NIAID) established the
Bioinformatics Resource Center (BRC) program to assist researchers with analyzing the …

Profiling the human intestinal environment under physiological conditions

D Shalon, RN Culver, JA Grembi, J Folz, PV Treit, H Shi… - Nature, 2023 - nature.com
The spatiotemporal structure of the human microbiome,, proteome and metabolome, reflects
and determines regional intestinal physiology and may have implications for disease. Yet …

IMG/VR v4: an expanded database of uncultivated virus genomes within a framework of extensive functional, taxonomic, and ecological metadata

AP Camargo, S Nayfach, IMA Chen… - Nucleic acids …, 2023 - academic.oup.com
Viruses are widely recognized as critical members of all microbiomes. Metagenomics
enables large-scale exploration of the global virosphere, progressively revealing the …

iPHoP: An integrated machine learning framework to maximize host prediction for metagenome-derived viruses of archaea and bacteria

S Roux, AP Camargo, FH Coutinho, SM Dabdoub… - PLoS …, 2023 - journals.plos.org
The extraordinary diversity of viruses infecting bacteria and archaea is now primarily studied
through metagenomics. While metagenomes enable high-throughput exploration of the viral …

BUSCO update: novel and streamlined workflows along with broader and deeper phylogenetic coverage for scoring of eukaryotic, prokaryotic, and viral genomes

M Manni, MR Berkeley, M Seppey… - Molecular biology …, 2021 - academic.oup.com
Methods for evaluating the quality of genomic and metagenomic data are essential to aid
genome assembly procedures and to correctly interpret the results of subsequent analyses …

Cryptic and abundant marine viruses at the evolutionary origins of Earth's RNA virome

AA Zayed, JM Wainaina, G Dominguez-Huerta… - Science, 2022 - science.org
Whereas DNA viruses are known to be abundant, diverse, and commonly key ecosystem
players, RNA viruses are insufficiently studied outside disease settings. In this study, we …

VirSorter2: a multi-classifier, expert-guided approach to detect diverse DNA and RNA viruses

J Guo, B Bolduc, AA Zayed, A Varsani… - Microbiome, 2021 - Springer
Background Viruses are a significant player in many biosphere and human ecosystems, but
most signals remain “hidden” in metagenomic/metatranscriptomic sequence datasets due to …