MAGIC populations in crops: current status and future prospects
Key message MAGIC populations present novel challenges and opportunities in crops due
to their complex pedigree structure. They offer great potential both for dissecting genomic …
to their complex pedigree structure. They offer great potential both for dissecting genomic …
Genome-wide association studies in mice
Genome-wide association studies (GWASs) have transformed the field of human genetics
and have led to the discovery of hundreds of genes that are implicated in human disease …
and have led to the discovery of hundreds of genes that are implicated in human disease …
The diversity outbred mouse population
Abstract The Diversity Outbred (DO) population is a heterogeneous stock derived from the
same eight founder strains as the Collaborative Cross (CC) inbred strains. Genetically …
same eight founder strains as the Collaborative Cross (CC) inbred strains. Genetically …
The genome architecture of the Collaborative Cross mouse genetic reference population
Collaborative Cross Consortium - Genetics, 2012 - academic.oup.com
Abstract The Collaborative Cross Consortium reports here on the development of a unique
genetic resource population. The Collaborative Cross (CC) is a multiparental recombinant …
genetic resource population. The Collaborative Cross (CC) is a multiparental recombinant …
Ten years of the collaborative cross
The February 2012 issues of GENETICS and G3: Genes, Genomes, Genetics present a
collection of articles reporting recent advances from the international Collaborative Cross …
collection of articles reporting recent advances from the international Collaborative Cross …
Status and access to the Collaborative Cross population
Abstract The Collaborative Cross (CC) is a panel of recombinant inbred lines derived from
eight genetically diverse laboratory inbred strains. Recently, the genetic architecture of the …
eight genetically diverse laboratory inbred strains. Recently, the genetic architecture of the …
GenomeMUSter mouse genetic variation service enables multitrait, multipopulation data integration and analysis
Hundreds of inbred mouse strains and intercross populations have been used to
characterize the function of genetic variants that contribute to disease. Thousands of disease …
characterize the function of genetic variants that contribute to disease. Thousands of disease …
Emerging genetics of COPD
A Berndt, AS Leme, SD Shapiro - EMBO molecular medicine, 2012 - embopress.org
Since the discovery of alpha‐1 antitrypsin in the early 1960s, several new genes have been
suggested to play a role in chronic obstructive pulmonary disease (COPD) pathogenesis …
suggested to play a role in chronic obstructive pulmonary disease (COPD) pathogenesis …
The Collaborative Cross as a resource for modeling human disease: CC011/Unc, a new mouse model for spontaneous colitis
AR Rogala, AP Morgan, AM Christensen, TJ Gooch… - Mammalian …, 2014 - Springer
Inflammatory bowel disease (IBD) is an immune-mediated condition driven by improper
responses to intestinal microflora in the context of environmental and genetic background …
responses to intestinal microflora in the context of environmental and genetic background …
Informatics resources for the Collaborative Cross and related mouse populations
The Collaborative Cross (CC) and the complementary Diversity Outbred (DO) population
were conceived as a platform for the next generation of studies of the genetic basis for …
were conceived as a platform for the next generation of studies of the genetic basis for …