Abstract Although the GABAergic benzodiazepines (BZDs) and Z-drugs (zolpidem,
zopiclone, and zaleplon) are FDA-approved for insomnia disorders with a strong evidence …

A common observation in EEG research is that consciousness vanishes with the
appearance of delta (1–4 Hz) waves, particularly when those waves are high amplitude …

Network dynamics have been proposed as a mechanistic substrate for the information
transfer across cortical and hippocampal circuits. However, little is known about the …

Brain activity during sleep is characterized by circuit-specific oscillations, including slow
waves, spindles and theta waves, which are nested in thalamocortical or hippocampal …

Extended wakefulness is associated with reduced performance and the build-up of sleep
pressure. In the cortex, this manifests as changes in network activity. These changes show …

Over more than a century of research has established the fact that sleep benefits the
retention of memory. In this review we aim to comprehensively cover the field of “sleep and …

Independent evidence associates β-amyloid pathology with both non-rapid eye movement
(NREM) sleep disruption and memory impairment in older adults. However, whether the …

Sleep is a complex physiological process that is regulated globally, regionally, and locally
by both cellular and molecular mechanisms. It occurs to some extent in all animals, although …

Background Alzheimer's disease (AD) pathology impairs cognitive function. Yet some
individuals with high amounts of AD pathology suffer marked memory impairment, while …

During sleep, cortical and subcortical structures within the brain engage in highly structured
oscillatory dynamics that can be observed in the electroencephalogram (EEG). The ability to …