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Cell death pathways in ischemic stroke and targeted pharmacotherapy
Ischemic stroke is one of the significant causes of morbidity and mortality, affecting millions
of people across the globe. Cell injury in the infarct region is an inevitable consequence of …
of people across the globe. Cell injury in the infarct region is an inevitable consequence of …
Beyond the hippocampus and the SVZ: adult neurogenesis throughout the brain
Convincing evidence has repeatedly shown that new neurons are produced in the
mammalian brain into adulthood. Adult neurogenesis has been best described in the …
mammalian brain into adulthood. Adult neurogenesis has been best described in the …
Mesenchymal stromal cell–derived small extracellular vesicles induce ischemic neuroprotection by modulating leukocytes and specifically neutrophils
Background and Purpose—Small extracellular vesicles (sEVs) obtained from mesenchymal
stromal cells (MSCs) were shown to induce neurological recovery after focal cerebral …
stromal cells (MSCs) were shown to induce neurological recovery after focal cerebral …
Final results of allogeneic adipose tissue–derived mesenchymal stem cells in acute ischemic stroke (AMASCIS): A phase II, randomized, double-blind, placebo …
Acute ischemic stroke is currently a major cause of disability despite improvement in
recanalization therapies. Stem cells represent a promising innovative strategy focused on …
recanalization therapies. Stem cells represent a promising innovative strategy focused on …
Efficacy of stem cell-based therapies for stroke
Stroke remains a prevalent disease with limited treatment options. Available treatments offer
little in the way of enhancing neurogenesis and recovery. Because of the limitations of …
little in the way of enhancing neurogenesis and recovery. Because of the limitations of …
Exosomes from human urine‐derived stem cells enhanced neurogenesis via miR‐26a/HDAC6 axis after ischaemic stroke
X Ling, G Zhang, Y **a, Q Zhu, J Zhang… - Journal of cellular …, 2020 - Wiley Online Library
Endogenous neurogenesis holds promise for brain repair and long‐term functional recovery
after ischaemic stroke. However, the effects of exosomes from human urine‐derived stem …
after ischaemic stroke. However, the effects of exosomes from human urine‐derived stem …
Human bone marrow-derived mesenchymal stem cells play a role as a vascular pericyte in the reconstruction of human BBB on the angiogenesis microfluidic chip
A blood-brain barrier (BBB) on a chip similar to the in vivo BBB is important for evaluating
the efficacy of reparative cell therapeutics for ischemic stroke in vitro. In this study, we …
the efficacy of reparative cell therapeutics for ischemic stroke in vitro. In this study, we …
Mesenchymal stem cells for regenerative medicine in central nervous system
M Li, H Chen, M Zhu - Frontiers in Neuroscience, 2022 - frontiersin.org
Mesenchymal stem cells (MSCs) are multipotent stem cells, whose paracrine and
immunomodulatory potential has made them a promising candidate for central nervous …
immunomodulatory potential has made them a promising candidate for central nervous …
[HTML][HTML] Mesenchymal stem-cell-derived exosomal miR-145 inhibits atherosclerosis by targeting JAM-A
W Yang, R Yin, X Zhu, S Yang, J Wang, Z Zhou… - … Therapy Nucleic Acids, 2021 - cell.com
Atherosclerosis is a chronic inflammatory disease associated with the development of
plaques that can be converted into an acute clinical event by thrombosis or plaque rupture …
plaques that can be converted into an acute clinical event by thrombosis or plaque rupture …
Dental pulp stem cells: an attractive alternative for cell therapy in ischemic stroke
Ischemic stroke is a major cause of disability and mortality worldwide, but effective
restorative treatments are very limited at present. Regenerative medicine research revealed …
restorative treatments are very limited at present. Regenerative medicine research revealed …