Oestradiol as a neuromodulator of learning and memory

LR Taxier, KS Gross, KM Frick - Nature Reviews Neuroscience, 2020 - nature.com
Although hormones such as glucocorticoids have been broadly accepted in recent decades
as general neuromodulators of memory processes, sex steroid hormones such as the potent …

New perspectives on sex differences in learning and memory

AW Fleischer, KM Frick - Trends in Endocrinology & Metabolism, 2023 - cell.com
Females have historically been disregarded in memory research, including the thousands of
studies examining roles for the hippocampus, medial prefrontal cortex, and amygdala in …

[HTML][HTML] Coming of age in the frontal cortex: The role of puberty in cortical maturation

K Delevich, M Klinger, NJ Okada, L Wilbrecht - Seminars in Cell & …, 2021 - Elsevier
Across species, adolescence is a period of growing independence that is associated with
the maturation of cognitive, social, and affective processing. Reorganization of neural …

Hippocampus‐based behavioral, structural, and molecular dynamics across the estrous cycle

D Rocks, M Kundakovic - Journal of neuroendocrinology, 2023 - Wiley Online Library
The activity of neurons in the rodent hippocampus contributes to diverse behaviors, with the
activity of ventral hippocampal neurons affecting behaviors related to anxiety and emotion …

[HTML][HTML] On the role of sex steroids in biological functions by classical and non-classical pathways. An update

M Pillerová, V Borbélyová, J Hodosy, V Riljak… - Frontiers in …, 2021 - Elsevier
The sex steroid hormones (SSHs) play several roles in regulation of various processes in
the cardiovascular, immune, muscular and neural systems. SSHs affect prenatal and …

Unexpected role of physiological estrogen in acute stress-induced memory deficits

RE Hokenson, AK Short, Y Chen, AL Pham… - Journal of …, 2021 - jneurosci.org
Stress may promote emotional and cognitive disturbances, which differ by sex. Adverse
outcomes, including memory disturbances, are typically observed following chronic stress …

The role of estrogen in anxiety-like behavior and memory of middle-aged female rats

E Renczés, V Borbélyová, M Steinhardt… - Frontiers in …, 2020 - frontiersin.org
Aging in women is associated with low estrogen, but also with cognitive decline and
affective disorders. Whether low estrogen is causally responsible for these behavioral …

TRPM3 in brain (patho) physiology

K Held, BI Tóth - Frontiers in Cell and Developmental Biology, 2021 - frontiersin.org
Already for centuries, humankind is driven to understand the physiological and pathological
mechanisms that occur in our brains. Today, we know that ion channels play an essential …

Prepubescent female rodents have enhanced hippocampal LTP and learning relative to males, reversing in adulthood as inhibition increases

AA Le, JC Lauterborn, Y Jia, W Wang, CD Cox… - Nature …, 2022 - nature.com
Multiple studies indicate that adult male rodents perform better than females on spatial
problems and have a lower threshold for long-term potentiation (LTP) of hippocampal CA3 …

G protein-coupled estrogen receptor: rapid effects on hippocampal-dependent spatial memory and synaptic plasticity

A Kumar, TC Foster - Frontiers in Endocrinology, 2020 - frontiersin.org
In the hippocampus, estrogen regulates gene transcription linked to neuronal growth,
neuroprotection, and the maintenance of memory function (–). The mechanism is likely to …