Traumatic brain injury and stroke are major causes of mortality and morbidity worldwide.
Unfortunately, almost all phase-III neuroprotective clinical trials for stroke and traumatic brain …

In its classic hormonal role, erythropoietin (EPO) is produced by the kidney and regulates
the number of erythrocytes within the circulation to provide adequate tissue oxygenation …

Allogeneic umbilical cord blood (UCB) has therapeutic potential for cerebral palsy (CP).
Concomitant administration of recombinant human erythropoietin (rhEPO) may boost the …

The growth factor erythropoietin (EPO) and erythropoietin receptors (EPOR) are expressed
in the nervous system. Neuronal expression of EPO and EPOR peaks during brain …

Erythropoietin (EPO), originally discovered as hematopoietic growth factor, has direct effects
on cells of the nervous system that make it a highly attractive candidate drug for …

Protein carbamylation refers to a nonenzymatic modification, which consists in the binding of
isocyanic acid on protein functional groups. This reaction is responsible for the alteration in …

Dementia is a syndrome associated with a wide range of clinical features including
progressive cognitive decline and patient inability to self-care. Due to rapidly increasing …

Background and Purpose—Erythropoietin (EPO) was explored regarding its suitability as a
candidate stroke drug in animal experimental studies. We performed a meta-analysis to …

Erythropoietin (EPO) is a glycoprotein hormone conventionally thought to be responsible
only in producing red blood cells in our body. However, with the discovery of the presence of …

Aging is a universal, intrinsic, and time-dependent biological decay that is linked to intricate
cellular processes including cellular senescence, telomere shortening, stem cell exhaustion …