Designing bioresponsive nanomaterials for intracellular self-assembly

S Chagri, DYW Ng, T Weil - Nature Reviews Chemistry, 2022 - nature.com
Supramolecular assemblies are essential components of living organisms. Cellular
scaffolds, such as the cytoskeleton or the cell membrane, are formed via secondary …

Biomedical polymers: synthesis, properties, and applications

WH Chen, QW Chen, Q Chen, C Cui, S Duan… - Science China …, 2022 - Springer
Biomedical polymers have been extensively developed for promising applications in a lot of
biomedical fields, such as therapeutic medicine delivery, disease detection and diagnosis …

Molecularly stimuli-responsive self-assembled peptide nanoparticles for targeted imaging and therapy

Y Zhou, Q Li, Y Wu, X Li, Y Zhou, Z Wang, H Liang… - ACS …, 2023 - ACS Publications
Self-assembly has emerged as an extensively used method for constructing biomaterials
with sizes ranging from nanometers to micrometers. Peptides have been extensively …

Trident molecule with nanobrush–nanoparticle–nanofiber transition property spatially suppresses tumor metastasis

G Gao, YW Jiang, W Zhan, X Liu, R Tang… - Journal of the …, 2022 - ACS Publications
Metastasis-induced high mortality of cancers urgently demands new approaches to
simultaneously inhibit primary tumor metastasis and distant tumor growth. Herein, by rational …

Intra-Lysosomal Peptide Assembly for the High Selectivity Index against Cancer

B Jana, S **, EM Go, Y Cho, D Kim, S Kim… - Journal of the …, 2023 - ACS Publications
Lysosomes remain powerful organelles and important targets for cancer therapy because
cancer cell proliferation is greatly dependent on effective lysosomal function. Recent studies …

Carrier-free nanomedicines for cancer treatment

LH Liu, XZ Zhang - Progress in Materials Science, 2022 - Elsevier
The last decade witnessed the great advances in the development of nanomedicines. As a
kind of attractive nanomedicine, carrier-free nanomedicines received extensive …

A comprehensive review on peptide-bearing biomaterials: From ex situ to in situ self-assembly

SY Qin, JQ Feng, YJ Cheng, WL Liu, AQ Zhang… - Coordination Chemistry …, 2024 - Elsevier
In the last few decades, we have witnessed the great advances of molecular self-assembly
in biomedical applications. Among the building blocks for molecular self-assembly, peptide …

Intelligent biomaterialomics: molecular design, manufacturing, and biomedical applications

Y Yi, HW An, H Wang - Advanced Materials, 2024 - Wiley Online Library
Materialomics integrates experiment, theory, and computation in a high‐throughput manner,
and has changed the paradigm for the research and development of new functional …

Intracellular condensates of oligopeptide for targeting lysosome and addressing multiple drug resistance of cancer

J Wang, L Hu, H Zhang, Y Fang, T Wang… - Advanced …, 2022 - Wiley Online Library
Biomolecular condensates have been demonstrated as a ubiquitous phenomenon in
biological systems and play a crucial role in controlling cellular functions. However, the …

Polymerization in living organisms

D Wu, J Lei, Z Zhang, F Huang, M Buljan… - Chemical Society …, 2023 - pubs.rsc.org
Vital biomacromolecules, such as RNA, DNA, polysaccharides and proteins, are
synthesized inside cells via the polymerization of small biomolecules to support and multiply …