Microbial engineering for the production of C 2–C 6 organic acids

Y Li, S Yang, D Ma, W Song, C Gao, L Liu… - Natural Product …, 2021 - pubs.rsc.org
Covering: up to the end of 2020 Organic acids, as building block compounds, have been
widely used in food, pharmaceutical, plastic, and chemical industries. Until now, chemical …

Recent Advances in the Metabolic Engineering of Klebsiella pneumoniae: A Potential Platform Microorganism for Biorefineries

MN Rhie, HT Kim, SY Jo, LL Chu, KA Baritugo… - Biotechnology and …, 2019 - Springer
The production of industrial chemicals from renewable biomass resources is a promising
solution to overcome the society's dependence on petroleum and to mitigate the pollution …

Processing techniques and microbial fermentation on microbial profile and chemical and sensory quality of the coffee beverage

MCS da Silva, JMR da Luz, TGR Veloso… - … Food Research and …, 2022 - Springer
Post-harvest processing and microbial fermentation of coffee fruits play an essential role in
the metabolites formation that influence the nutritional and sensory quality of the beverage …

Lysine acetylation of Escherichia coli lactate dehydrogenase regulates enzyme activity and lactate synthesis

M Liu, M Huo, C Liu, L Guo, Y Ding, Q Ma… - … in Bioengineering and …, 2022 - frontiersin.org
As an evolutionarily conserved posttranslational modification, protein lysine acetylation
plays important roles in many physiological and metabolic processes. However, there are …

Engineering CRISPR interference system in Klebsiella pneumoniae for attenuating lactic acid synthesis

J Wang, P Zhao, Y Li, L Xu, P Tian - Microbial cell factories, 2018 - Springer
Background Klebsiella pneumoniae is a promising industrial species for bioproduction of
bulk chemicals such as 1, 3-propanediol, 2, 3-butanediol and 3-hydroxypropionic acid (3 …

[HTML][HTML] A novel approach to enhance high optically active L-lactate production from food waste by landfill leachate

W Zhang, J Shi, Y Li, Y Ma, AK Khanzada… - Journal of …, 2024 - Elsevier
The recycling of food waste (FW) through anaerobic fermentation into lactic acid (LA), with
two isomers L-LA and D-LA, aligns with the principles of a bio-based circular economy …

Combining metabolic engineering and evolutionary adaptation in Klebsiella oxytoca KMS004 to significantly improve optically pure D-(−)-lactic acid yield and specific …

S In, P Khunnonkwao, N Wong, C Phosiran… - Applied Microbiology …, 2020 - Springer
In this study, K. oxytoca KMS004 (Δ adhE Δ pta-ackA) was further reengineered by the
deletion of frdABCD and pflB genes to divert carbon flux through D-(−)-lactate production …

Energy-and cost-effective non-sterilized fermentation of 2, 3-butanediol by an engineered Klebsiella pneumoniae OU7 with an anti-microbial contamination system

ZW Guo, XY Ou, P Xu, HF Gao, LY Zhang, MH Zong… - Green …, 2020 - pubs.rsc.org
Microbial contamination is a serious challenge that needs to be overcome for the successful
biosynthesis of 2, 3-butanediol (2, 3-BD). However, traditional strategies such as antibiotic …

[HTML][HTML] The production of D-lactic acid by fermentation from the waste newspapers recycling as the carbon source

S Zhang, Y Liu, C Zhou, Z Li, W Gao - Environmental Technology & …, 2024 - Elsevier
Abstract D-lactic acid (D-LA) is an important substance, which has been used in various end-
use industries, including pharmaceuticals, food and milk beverages. Lignocellulose is a …

Adaptive Evolution for the Efficient Production of High-Quality d-Lactic Acid Using Engineered Klebsiella pneumoniae

B Jiang, J Liu, J Wang, G Zhao, Z Zhao - Microorganisms, 2024 - mdpi.com
D-Lactic acid serves as a pivotal platform chemical in the production of poly D-lactic acid
(PDLA) and other value-added products. This compound can be synthesized by certain …