During evolution, individuals whose brains and bodies functioned well in a fasted state were
successful in acquiring food, enabling their survival and reproduction. With fasting and …

The relationship between body mass index (BMI)(in midlife and late‐life) and dementia was
investigated in meta‐analyses of 16 articles reporting on 15 prospective studies. Follow‐ups …

Abstract Objective (Background): Alzheimer's disease (AD), clinically characterized by the
progressive neurodegenerative condition and cognitive impairment, is one of the main …

Despite a wealth of clinical data showing an association between inflammation and
degenerative disorders in the elderly, the immune sensors that causally link systemic …

Frailty, a critical intermediate status of the aging process that is at increased risk for negative
health-related events, includes physical, cognitive, and psychosocial domains or …

Alzheimer's disease (AD) is the most common form of dementia in the elderly followed by
vascular dementia. In addition to clinically diagnosed dementia, cognitive dysfunction has …

Cross-talk between adipose tissue and central nervous system (CNS) underlies the
increased risk of obese people to develop brain diseases such as cognitive and mood …

The latest studies have indicated a strong relationship between systemic insulin resistance
(IR) and higher incidence of neurodegeneration, dementia, and mild cognitive impairment …

Background To examine the effect of multicomponent exercise program on memory function
in older adults with mild cognitive impairment (MCI), and identify biomarkers associated with …

Alzheimer's disease (AD) should be regarded as a degenerative metabolic disease caused
by brain insulin resistance and deficiency, and overlap** with the molecular, biochemical …