A molecular motor is made of either a single macromolecule or a macromolecular complex.
Just like their macroscopic counterparts, molecular motors “transduce” input energy into …

At the onset of division, the cell forms a spindle, a precise self-constructed micromachine
composed of microtubules and the associated proteins, which divides the chromosomes …

One of the major challenges in modern biology is to understand how the molecular
components of a living cell operate in a highly noisy environment. What are the specific …

Many cellular processes require molecular motors to produce motion and forces. Single
molecule experiments have led to a precise description of how a motor works. Under most …

Dynamic processes in living cells are highly organized in space and time. Unraveling the
underlying molecular mechanisms of spatiotemporal pattern formation remains one of the …

Multipolar spindles are very rare in normal tissues, but they are much more prevalent in
many tumors, which might be induced by the mechanical confinements from overcrowding …

Individual dynamic microtubules can generate pushing or pulling forces when their growing
or shrinking ends are in contact with cellular objects such as the cortex or chromosomes …

Intracellular transport along cytoskeletal filaments is often mediated by two teams of
molecular motors that pull on the same cargo and move in opposite directions along the …

Meiotic nuclear oscillations in the fission yeast Schizosaccharomyces pombe are crucial for
proper chromosome pairing and recombination. We report a mechanism of these …

During metaphase, chromosomes are aligned in a lineup at the equatorial plane of the
spindle to ensure synchronous poleward movement of chromatids in anaphase and proper …