Global Literature Analysis of Organoid and Organ‐on‐Chip Research

J Shoji, RP Davis, CL Mummery… - Advanced healthcare …, 2024 - Wiley Online Library
Organoids and cells in organ‐on‐chip platforms replicate higher‐level anatomical,
physiological, or pathological states of tissues and organs. These technologies are widely …

Cellular and molecular control of vertebrate somitogenesis

Y Miao, O Pourquié - Nature Reviews Molecular Cell Biology, 2024 - nature.com
Segmentation is a fundamental feature of the vertebrate body plan. This metameric
organization is first implemented by somitogenesis in the early embryo, when paired …

Self-patterning of human stem cells into post-implantation lineages

M Pedroza, SI Gassaloglu, N Dias, L Zhong, TCJ Hou… - Nature, 2023 - nature.com
Investigating human development is a substantial scientific challenge due to the technical
and ethical limitations of working with embryonic samples. In the face of these difficulties …

Modeling post-implantation stages of human development into early organogenesis with stem-cell-derived peri-gastruloids

L Liu, S Oura, Z Markham, JN Hamilton, RM Skory, L Li… - Cell, 2023 - cell.com
In vitro stem cell models that replicate human gastrulation have been generated, but they
lack the essential extraembryonic cells needed for embryonic development, morphogenesis …

Dissecting peri-implantation development using cultured human embryos and embryo-like assembloids

Z Ai, B Niu, Y Yin, L ** human organs via embryo models and chimeras
J Wu, J Fu - Cell, 2024 - cell.com
Develo** functional organs from stem cells remains a challenging goal in regenerative
medicine. Existing methodologies, such as tissue engineering, bioprinting, and organoids …

Technical challenges of studying early human development

PJ Rugg-Gunn, N Moris, PPL Tam - Development, 2023 - journals.biologists.com
Recent years have seen exciting progress across human embryo research, including new
methods for culturing embryos, transcriptional profiling of embryogenesis and gastrulation …