Heteroatoms as well as heterocyclic scaffolds are frequently present as the common cores in
a plethora of active pharmaceuticals natural products. Statistically, more than 85% of all …

Triazole-based drugs are a dynamic class of compounds exhibiting extensive therapeutic
potential. This comprehensive review explores the synthesis, application, FDA approvals …

This review highlights the nature, characteristics, properties, pharmacological differences
between different types of benzodiazepines, the mechanism of action in the central nervous …

With the progressive and ever-increasing antibacterial resistance pathway, the need for
novel antibiotic design becomes critical. Sulfonamides are one of the more effective …

GABAA receptor modulators are structurally almost as diverse as their target protein. A
plethora of heterocyclic scaffolds has been described as modulating this extremely important …

Estazolam (Z1) and related derivatives, adinazolam (Z2), alprazolam (Z3), 4-
hydroxyalprazolam (Z4) and triazolam (Z5) have been studied by using various …

Benzodiazepines, a well-studied class of seven-membered aromatic heterocycles
containing two nitrogen atoms, have shown great promise as therapeutic agents. Efficient …

Several phthalazine derivatives were synthesized by the one-pot three-component
condensation in good to high yields in the presence of diatomite-SO _ 3 H SO 3 H as a solid …

1, 2, 4-Triazoles are ubiquitous in pharmaceuticals, natural products, coordination chemistry,
agrochemicals, and materials science research. Herein we report a practical regioselective …

A one-pot synthesis of triazolobenzodiazepine-containing polycyclic compounds is
introduced. The reaction process involves a decarboxylative three-component [3+ 2] …