The evaluation and management of neonatal coagulation disorders

MA Saxonhouse, MJ Manco-Johnson - Seminars in perinatology, 2009 - Elsevier
Neonatal hemostatic abnormalities can present diagnostic and therapeutic challenges to the
physician. Developmental deficiencies and/or increases of certain coagulation proteins …

Association between MTHFR 677C> T polymorphism and vascular complications in sickle cell disease: A meta-analysis

B Lakkakula - Transfusion Clinique et Biologique, 2019 - Elsevier
Sickle cell disease (SCD) is considered as a vascular disease due to its chronic vascular
manifestations such as leg ulcers, priapism, acute chest syndrome (ACS), stroke …

Association between micronutrients and hyperhomocysteinemia: a case-control study in Northeast China

C Sun, D Ding, Z Wen, C Zhang, J Kong - Nutrients, 2023 - mdpi.com
Hyperhomocysteinemia (HHcy) is an independent risk factor for cardiovascular and
cerebrovascular diseases where the plasma homocysteine (Hcy) concentration exceeds 15 …

Analysis of genetic polymorphism of methylenetetrahydrofolate reductase in a large ethnic Hakka population in southern China

P Zhao, J Hou, H Wu, M Zhong - Medicine, 2018 - journals.lww.com
Methylenetetrahydrofolate reductase (MTHFR) catalyzes conversion of methylene
tetrahydrofolate to methylte trahydrofolate. MTHFR C677T polymorphism has been regarded …

Heterozygous methylenetetrahydrofolate reductase 677C-T gene mutation with mild hyperhomocysteinemia associated with intrauterine iliofemoral artery thrombosis

B Alioglu, E Ozyurek, A Tarcan, FB Atac… - Blood coagulation & …, 2006 - journals.lww.com
Neonatal thrombosis is a serious event that can cause mortality or severe morbidity.
Newborn-related factors, including genetic prothrombotic risk factors, may affect the …

MTHFR 677 C> T Gene Polymorphism is Associated with Large for Gestational Age Infants

R Akcılar, EE Yalınbaş, F Mutlu - Fetal and Pediatric Pathology, 2024 - Taylor & Francis
Background The aim of this study was to investigate the methylenetetrahydrofolate
reductase (MTHFR) 677 C> T gene polymorphism in term infants born small (SGA) …

Association between the MTHFR A1298C polymorphism and increased risk of acute myeloid leukemia in Brazilian children

FJ da Costa Ramos, MT Cartaxo Muniz… - Leukemia & …, 2006 - Taylor & Francis
Methylenetetrahydrofolate reductase (MTHFR) is an essential enzyme in the metabolism of
folate. The presence of polymorphisms that reduce the activity of MTHFR has been linked to …

Folate, vitamin B12 and total homocysteine levels in neonates from Brazil

FD Couto, LMO Moreira, DB Dos Santos… - European journal of …, 2007 - nature.com
Objective: To determine folates, vitamin B12 and total homocysteine levels among neonates
from mothers of low or high socioeconomic status. Design: We carried out a cross-sectional …

Pharmacogenetic studies in the Brazilian population

G Suarez-Kurtz, SDJ Pena - Pharmacogenomics in admixed …, 2007 - books.google.com
B y Europeans, levels virtue of genomic of Africans being diversity the and product
Amerindians, and several of the peculiarities genetic the Brazilian admixture in its …

Methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and high plasma homocysteine in chronic hepatitis C (CHC) infected patients from the Northeast …

ERF Siqueira, CPMS Oliveira, MTC Muniz, F Silva… - Nutrition Journal, 2011 - Springer
Abstract Background/Aim Hyperhomocysteinemia due to Methylenetetrahydrofolate
Reductase (MTHFR) gene, in particular the C677T (Ala222Val) polymorphism were recently …