Molecular and nonmolecular diagnostic methods for invasive fungal infections

M Arvanitis, T Anagnostou, BB Fuchs… - Clinical microbiology …, 2014 - Am Soc Microbiol
Invasive fungal infections constitute a serious threat to an ever-growing population of
immunocompromised individuals and other individuals at risk. Traditional diagnostic …

Aspergillus Polymerase Chain Reaction: Systematic Review of Evidence for Clinical Use in Comparison With Antigen Testing

PL White, JR Wingard, S Bretagne… - Clinical Infectious …, 2015 - academic.oup.com
Background. Aspergillus polymerase chain reaction (PCR) was excluded from the European
Organisation for the Research and Treatment of Cancer/Mycoses Study Group …

Identification of mycoses in develo** countries

A Arastehfar, BL Wickes, M Ilkit, DH Pincus… - Journal of Fungi, 2019 - mdpi.com
Extensive advances in technology offer a vast variety of diagnostic methods that save time
and costs, but identification of fungal species causing human infections remains challenging …

An overview of using fungal DNA for the diagnosis of invasive mycoses

PL White, A Alanio, L Brown, M Cruciani… - Expert Review of …, 2022 - Taylor & Francis
Introduction Fungal PCR has undergone considerable standardization and, together with
the availability of commercial assays, external quality assessment schemes, and extensive …

Diagnosis of aspergillosis by PCR: clinical considerations and technical tips

RA Barnes, PL White, CO Morton, TR Rogers… - Medical …, 2018 - academic.oup.com
Standardization of Aspergillus polymerase chain reaction (PCR) protocols has progressed,
and analytical validity of blood-based assays has been formally established. It remains …

Molecular diagnosis of invasive aspergillosis and detection of azole resistance by a newly commercialized PCR kit

E Dannaoui, F Gabriel, M Gaboyard… - Journal of clinical …, 2017 - Am Soc Microbiol
Aspergillus fumigatus is the main species responsible for aspergillosis in humans. The
diagnosis of aspergillosis remains difficult, and the rapid emergence of azole resistance in …

Aspergillus Polymerase Chain Reaction—An Update on Technical Recommendations, Clinical Applications, and Justification for Inclusion in the Second Revision of …

PL White, S Bretagne, AM Caliendo… - Clinical Infectious …, 2021 - academic.oup.com
Aspergillus polymerase chain reaction testing of blood and respiratory samples has recently
been included in the second revision of the EORTC/MSGERC definitions for classifying …

Consensus guidelines for the use of empiric and diagnostic‐driven antifungal treatment strategies in haematological malignancy, 2014

CO Morrissey, NM Gilroy, N Macesic… - Internal Medicine …, 2014 - Wiley Online Library
Invasive fungal disease (IFD) causes significant morbidity and mortality in patients
undergoing allogeneic haemopoietic stem cell transplantation or chemotherapy for …

Evaluation of a commercially developed semiautomated PCR–surface-enhanced Raman scattering assay for diagnosis of invasive fungal disease

PL White, SJ Hibbitts, MD Perry, J Green… - Journal of clinical …, 2014 - Am Soc Microbiol
Nonculture-based tests are gaining popularity in the diagnosis of invasive fungal disease
(IFD), but PCR is excluded from disease-defining criteria because of limited standardization …

The current management landscape: aspergillosis

JA Maertens, O Blennow, RF Duarte… - Journal of Antimicrobial …, 2016 - academic.oup.com
Diagnosing invasive aspergillosis (IA) has long been challenging due to the inability to
culture the causal Aspergillus agent from blood or other body fluids. This shortcoming has …