Tumor-activated carrier-free prodrug nanoparticles for targeted cancer Immunotherapy: Preclinical evidence for safe and effective drug delivery

MK Shim, S Yang, IC Sun, K Kim - Advanced Drug Delivery Reviews, 2022 - Elsevier
As immunogenic cell death (ICD) inducers initiating antitumor immune responses, certain
chemotherapeutic drugs have shown considerable potential to reverse the …

mRNA Cancer vaccines: construction and boosting strategies

X Liu, P Huang, R Yang, H Deng - ACS nano, 2023 - ACS Publications
In late 2020, the US Food and Drug Administration (FDA) approved a lipid-based mRNA
vaccine for the prevention of COVID-19, which has pushed this field to be more closely …

Drug delivery by ultrasound-responsive nanocarriers for cancer treatment

K Entzian, A Aigner - Pharmaceutics, 2021 - mdpi.com
Conventional cancer chemotherapies often exhibit insufficient therapeutic outcomes and
dose-limiting toxicity. Therefore, there is a need for novel therapeutics and formulations with …

[HTML][HTML] A hydrogen peroxide economizer for on-demand oxygen production-assisted robust sonodynamic immunotherapy

Q Jiang, B Qiao, X Lin, J Cao, N Zhang, H Guo… - Theranostics, 2022 - ncbi.nlm.nih.gov
The outcome of sonodynamic immunotherapy is significantly limited by tumor hypoxia. To
overcome this obstacle, one common solution is to catalyze the conversion of endogenous …

Mitochondria-targeted and ultrasound-activated nanodroplets for enhanced deep-penetration sonodynamic cancer therapy

L Zhang, H Yi, J Song, J Huang, K Yang… - … applied materials & …, 2019 - ACS Publications
Sonodynamic therapy (SDT), a promising alternative for cancer therapy, utilizes a
sonosensitizer combined with ultrasound (US) irradiation to damage tumor cells/tissues for …

Bacteria-based bioactive materials for cancer imaging and therapy

Y Chen, ZH Li, X Zeng, XZ Zhang - Advanced Drug Delivery Reviews, 2023 - Elsevier
Owing to the unique biological functions, bacteria as biological materials have been widely
used in biomedical field. With advances in biotechnology and nanotechnology, various …

Graphene quantum dots-mediated theranostic penetrative delivery of drug and photolytics in deep tumors by targeted biomimetic nanosponges

SY Sung, YL Su, W Cheng, PF Hu, CS Chiang… - Nano …, 2018 - ACS Publications
Dual-targeted delivery of drugs and energy by nanohybrids can potentially alleviate side
effects and improve the unique features required for precision medicine. To realize this aim …

Temperature‐feedback nanoplatform for NIR‐II penta‐modal imaging‐guided synergistic photothermal therapy and CAR‐NK immunotherapy of lung cancer

M Xu, B Xue, Y Wang, D Wang, D Gao, S Yang, Q Zhao… - Small, 2021 - Wiley Online Library
In this study, to visually acquire all‐round structural and functional information of lung cancer
while performing synergistic photothermal therapy (PTT) and tumor‐targeting …

Ultrasound triggered conversion of porphyrin/camptothecin-fluoroxyuridine triad microbubbles into nanoparticles overcomes multidrug resistance in colorectal cancer

M Chen, X Liang, C Gao, R Zhao, N Zhang, S Wang… - ACS …, 2018 - ACS Publications
Multidrug resistance remains one of the main obstacles to efficient chemotherapy of
colorectal cancer. Herein, an efficient combination therapeutic strategy is proposed based …

Phase-shift nanodroplets as an emerging sonoresponsive nanomaterial for imaging and drug delivery applications

W Zhang, Y Shi, S Abd Shukor, A Vijayakumaran… - Nanoscale, 2022 - pubs.rsc.org
Nanodroplets–emerging phase-changing sonoresponsive materials–have attracted
substantial attention in biomedical applications for both tumour imaging and therapeutic …