Tumor-activated carrier-free prodrug nanoparticles for targeted cancer Immunotherapy: Preclinical evidence for safe and effective drug delivery
As immunogenic cell death (ICD) inducers initiating antitumor immune responses, certain
chemotherapeutic drugs have shown considerable potential to reverse the …
chemotherapeutic drugs have shown considerable potential to reverse the …
mRNA Cancer vaccines: construction and boosting strategies
In late 2020, the US Food and Drug Administration (FDA) approved a lipid-based mRNA
vaccine for the prevention of COVID-19, which has pushed this field to be more closely …
vaccine for the prevention of COVID-19, which has pushed this field to be more closely …
Drug delivery by ultrasound-responsive nanocarriers for cancer treatment
K Entzian, A Aigner - Pharmaceutics, 2021 - mdpi.com
Conventional cancer chemotherapies often exhibit insufficient therapeutic outcomes and
dose-limiting toxicity. Therefore, there is a need for novel therapeutics and formulations with …
dose-limiting toxicity. Therefore, there is a need for novel therapeutics and formulations with …
[HTML][HTML] A hydrogen peroxide economizer for on-demand oxygen production-assisted robust sonodynamic immunotherapy
Q Jiang, B Qiao, X Lin, J Cao, N Zhang, H Guo… - Theranostics, 2022 - ncbi.nlm.nih.gov
The outcome of sonodynamic immunotherapy is significantly limited by tumor hypoxia. To
overcome this obstacle, one common solution is to catalyze the conversion of endogenous …
overcome this obstacle, one common solution is to catalyze the conversion of endogenous …
Mitochondria-targeted and ultrasound-activated nanodroplets for enhanced deep-penetration sonodynamic cancer therapy
L Zhang, H Yi, J Song, J Huang, K Yang… - … applied materials & …, 2019 - ACS Publications
Sonodynamic therapy (SDT), a promising alternative for cancer therapy, utilizes a
sonosensitizer combined with ultrasound (US) irradiation to damage tumor cells/tissues for …
sonosensitizer combined with ultrasound (US) irradiation to damage tumor cells/tissues for …
Bacteria-based bioactive materials for cancer imaging and therapy
Y Chen, ZH Li, X Zeng, XZ Zhang - Advanced Drug Delivery Reviews, 2023 - Elsevier
Owing to the unique biological functions, bacteria as biological materials have been widely
used in biomedical field. With advances in biotechnology and nanotechnology, various …
used in biomedical field. With advances in biotechnology and nanotechnology, various …
Graphene quantum dots-mediated theranostic penetrative delivery of drug and photolytics in deep tumors by targeted biomimetic nanosponges
SY Sung, YL Su, W Cheng, PF Hu, CS Chiang… - Nano …, 2018 - ACS Publications
Dual-targeted delivery of drugs and energy by nanohybrids can potentially alleviate side
effects and improve the unique features required for precision medicine. To realize this aim …
effects and improve the unique features required for precision medicine. To realize this aim …
Temperature‐feedback nanoplatform for NIR‐II penta‐modal imaging‐guided synergistic photothermal therapy and CAR‐NK immunotherapy of lung cancer
In this study, to visually acquire all‐round structural and functional information of lung cancer
while performing synergistic photothermal therapy (PTT) and tumor‐targeting …
while performing synergistic photothermal therapy (PTT) and tumor‐targeting …
Ultrasound triggered conversion of porphyrin/camptothecin-fluoroxyuridine triad microbubbles into nanoparticles overcomes multidrug resistance in colorectal cancer
Multidrug resistance remains one of the main obstacles to efficient chemotherapy of
colorectal cancer. Herein, an efficient combination therapeutic strategy is proposed based …
colorectal cancer. Herein, an efficient combination therapeutic strategy is proposed based …
Phase-shift nanodroplets as an emerging sonoresponsive nanomaterial for imaging and drug delivery applications
Nanodroplets–emerging phase-changing sonoresponsive materials–have attracted
substantial attention in biomedical applications for both tumour imaging and therapeutic …
substantial attention in biomedical applications for both tumour imaging and therapeutic …