The incretin hormones glucose‐dependent insulinotropic polypeptide (GIP) and glucagon‐
like peptide‐1 (GLP‐1) have their main physiological role in augmenting insulin secretion …

The efficacy of Roux-en-Y gastric-bypass (RYGB) and other bariatric surgeries in the
management of obesity and type 2 diabetes mellitus and novel developments in …

Olfactory and taste receptors are expressed primarily in the nasal olfactory epithelium and
gustatory taste bud cells, where they transmit real-time sensory signals to the brain …

Until recently, the general belief was that non-nutritive sweeteners (NNSs) were healthy
sugar substitutes because they provide sweet taste without calories or glycemic effects …

Recent progress in unravelling the nutrient-sensing mechanisms in the taste buds of the
tongue has triggered studies on the existence and role of chemosensory cells in the gut …

Olfactory receptors (ORs) provide the molecular basis for the detection of volatile odorant
molecules by olfactory sensory neurons. The OR supergene family encodes G-protein …

Key points• In intestine, nutrients including glucose and amino acids and non‐nutrients
including bile acids increase secretion of anti‐diabetic gut peptides such as gluco …

Thirty‐six patients with type 2 diabetes mellitus (T2DM) were randomized 1: 1: 1 to receive a
once‐daily oral dose of placebo or 150 or 300 mg of the dual SGLT1/SGLT2 inhibitor …

The homoeostatic regulation of metabolism is highly complex and involves multiple inputs
from both the nervous and endocrine systems. The gut is the largest endocrine organ in our …

Sugar reduction is a major technical challenge for the food industry to address in response
to public health concerns regarding the amount of added sugars in foods. This paper …