Salmonella infection: Interplay between the bacteria and host immune system

JR Kurtz, JA Goggins, JB McLachlan - Immunology letters, 2017 - Elsevier
Salmonella infection causes morbidity and mortality throughout the world with the host
immune response varying depending on whether the infection is acute and limited, or …

miR‐155: an ancient regulator of the immune system

E Vigorito, S Kohlhaas, D Lu… - Immunological reviews, 2013 - Wiley Online Library
Micro RNA s (mi RNA s) are a newly recognized class of regulatory genes which repress the
expression of protein‐coding genes. Numerous studies have uncovered a complex role for …

Salmonella typhimurium aroA-infection in gene-targeted immunodeficient mice: major role of CD4+ TCR-alpha beta cells and IFN-gamma in bacterial clearance …

J Hess, C Ladel, D Miko… - Journal of immunology …, 1996 - journals.aai.org
Due to the dependency on aromatic precursors, the growth of Salmonella typhimurium aroA-
is limited in immunocompetent mice. Here we show that H-21-A beta-/-mice (lacking MHC …

Signaling via the MyD88 adaptor protein in B cells suppresses protective immunity during Salmonella typhimurium infection

P Neves, V Lampropoulou, E Calderon-Gomez, T Roch… - Immunity, 2010 - cell.com
The myeloid differentiation primary response gene 88 (Myd88) is critical for protection
against pathogens. However, we demonstrate here that MyD88 expression in B cells inhibits …

Membrane vesicles are immunogenic facsimiles of Salmonella typhimurium that potently activate dendritic cells, prime B and T cell responses, and stimulate protective …

RC Alaniz, BL Deatherage, JC Lara… - The Journal of …, 2007 - journals.aai.org
Gram-negative bacteria produce membrane vesicles (MVs) from their outer membrane
during growth, although the mechanism for MV production and the advantage that MVs …

Vaccines against invasive Salmonella disease: Current status and future directions

CA MacLennan, LB Martin, F Micoli - Human vaccines & …, 2014 - Taylor & Francis
Though primarily enteric pathogens, Salmonellae are responsible for a considerable yet
under-appreciated global burden of invasive disease. In South and South-East Asia, this …

SALMONELLOSIS: Host Immune Responses and Bacterial Virulence Determinants1

BD Jones, S Falkow - Annual review of immunology, 1996 - annualreviews.org
▪ Abstract The lifestyle of bacterial pathogens requires them to establish infection in the face
of host immunity. Upon entering a potential host, a variety of interactions are initiated, the …

Immune response to infection with Salmonella typhimurium in mice

HW Mittrücker, SHE Kaufmann - Journal of leukocyte biology, 2000 - academic.oup.com
Infection of mice with Salmonella typhimurium results in systemic infection and a disease
similar to that seen in humans after infection with S. typhi. The innate immune system can …

Immunity to salmonellosis

G Dougan, V John, S Palmer… - Immunological …, 2011 - Wiley Online Library
Salmonella enterica is a genetically broad species harboring isolates that display
considerable antigenic heterogeneity and significant differences in virulence potential …

Invasive Nontyphoidal Salmonella Disease in Africa

JJ Gilchrist, CA MacLennan - EcoSal Plus, 2019 - Am Soc Microbiol
Nontyphoidal salmonellae (NTS) are a major cause of invasive (iNTS) disease in sub-
Saharan Africa, manifesting as bacteremia and meningitis. Available epidemiological data …