Physical exercise (PE) improves physical performance, mental status, general health, and
well-being. It does so by affecting many mechanisms at the cellular and molecular level. PE …

Lactate (La−) has long been at the center of controversy in research, clinical, and athletic
settings. Since its discovery in 1780, La− has often been erroneously viewed as simply a …

Die vorliegende Schrift verfolgt das Ziel, das hohe Alter aus zwei Perspektiven zu
betrachten: einer Verletzlichkeits-und einer Reife-oder Potenzialperspektive. Sie versteht …

As the population ages due to demographic trends and gains in life expectancy, the
incidence and prevalence of dementia increases, and the need to understand the etiology …

An active lifestyle is crucial to maintain health into old age; inversely, sedentariness has
been linked to an elevated risk for many chronic diseases. The discovery of myokines …

Abstract “The Scaffolding Theory of Aging and Cognition (STAC)”, proposed in 2009, is a
conceptual model of cognitive aging that integrated evidence from structural and functional …

Studies supporting the notion that physical activity and exercise can help alleviate the
negative impact of age on the body and the mind abound. This literature review provides an …

Depression is a syndrome of stress-and emotion-dysregulation, involving compromised
structural integrity of frontal-limbic networks. Meta-analytic evidence indicates that volumetric …

Highlights•Physical activity is an effective method of capitalizing on brain plasticity.•Some
brain areas and cognitive domains are more consistently influenced by physical activity than …

The population of aged individuals is increasing worldwide and this has significant health
and socio-economic implications. Clinical and experimental studies on aging have …