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Facile one-pot multicomponent synthesis of peptoid based gelators as novel scaffolds for drug incorporation and pH-sensitive release
Infections caused by bacteria are the primary cause of illness and death globally, and
antibiotics are the most commonly used medications to treat them. However, there are …
antibiotics are the most commonly used medications to treat them. However, there are …
Supramolecular organo/hydrogel-fabricated long alkyl chain α-amidoamides as a smart soft material for pH-responsive curcumin release
Low-molecular-mass gelators, due to their excellent biocompatibility, low toxicological
profile, innate biodegradability and ease of fabrication have garnered significant interest as …
profile, innate biodegradability and ease of fabrication have garnered significant interest as …
Application of inorganic nanomaterials in transdermal and topical medications: influential parameters, opportunities and challenges
Recent advances in nanotechnology are expected to assist scientists in solving many key
obstacles in biological complications. During the last decade, a great deal of research …
obstacles in biological complications. During the last decade, a great deal of research …
Atom-economical synthesis, antimicrobial assessment, and molecular dynamics of indole-derived peptidomimetics for improved therapeutic insights
The emergence of multi-drug resistant strains spanning bacteria, fungi, viruses, and
parasites poses a severe threat to public health and the economy. Tackling antimicrobial …
parasites poses a severe threat to public health and the economy. Tackling antimicrobial …
Anti-quorum sensing activity of α-amidoamides against Agrobacterium tumefaciensNT1: Insights from molecular docking and dynamic investigations to synergistic …
A unique approach is imperative for the development of drugs aimed at inhibiting various
stages of infection, rather than solely focusing on bacterial viability. Among the array of …
stages of infection, rather than solely focusing on bacterial viability. Among the array of …
N‐Hydroxyalkanamide Based Organo/hydrogels as Novel Scaffolds for pH‐Dependent Metronidazole and Theophylline Release
The traditional delivery of metronidazole and theophylline presents challenges like bitter
taste, variable absorption, and side effects. However, gel‐based systems offer advantages …
taste, variable absorption, and side effects. However, gel‐based systems offer advantages …
Photopatterned Hybrid Supramolecular/Polymer Hydrogels for Controlled Heparin Release and Stem Cell Growth
Á López‐Acosta, PRA Chivers, CC Piras… - …, 2024 - Wiley Online Library
This paper reports hybrid gels combining a low‐molecular‐weight gelator (LMWG) and a
photoinitiated crosslinked polymer gel (PG). The presence of the PG enhanced the stiffness …
photoinitiated crosslinked polymer gel (PG). The presence of the PG enhanced the stiffness …
Fabrication of targeted PDA-Hemin-Dox-FA nanoplatform for enhanced chemodynamic therapy synergized with chemo/photothermal therapy
Y Wang, N Zheng, Z Zhang, H Ma, Y Wei - Colloids and Surfaces A …, 2023 - Elsevier
Chemotherapy (CT) is widely used in clinical practice due to its simple and convenient
steps, but its characteristics of systemic administration also results in a lack of targeting and …
steps, but its characteristics of systemic administration also results in a lack of targeting and …
Environmentally benign self-assembled biopolymer-peptoid nanosilver composite hybrid gel beads via ion-crosslinking for antimicrobial and catalytic applications
Silver nanoparticles are gaining significant attention due to their exceptional versatility
arising from their unique combination of size, surface properties, and inherent reactivity. This …
arising from their unique combination of size, surface properties, and inherent reactivity. This …
Unveiling Gelation and Antimicrobial Potentials of α‐Acyloxy Carboxamides: Findings from Experimental and Theoretical Approach
S Sebastian, M Kumar, F Hussain, S Rathore… - ChemMedChem - Wiley Online Library
Multicomponent reactions have long been recognized as some of the most versatile tools in
organic chemistry, with extensive applications in biomedical science and the pharmaceutical …
organic chemistry, with extensive applications in biomedical science and the pharmaceutical …