Globally, enteropathogenic bacteria are a major cause of morbidity and mortality. 1-3
Campylobacter, Salmonella, Shiga-toxin-producing Escherichia coli, and Listeria are among …

Over the past decade, the association between oral health, intestinal microbiota, and
systemic diseases has been further validated. Some oral microbial species have been …

Oxidative stress, caused by excessive production of reactive oxygen species (ROS), plays a
crucial role in the occurrence and development of ulcerative colitis (UC). We developed …

Intestinal epithelial cells (IECs) constitute a critical first line of defense against microbes.
While IECs are known to respond to various microbial signals, the precise upstream cues …

Besides its crucial function in nutrient absorbance and as barrier against the microbiota, the
gut epithelium is essential for sensing pathogenic insults and mounting of an appropriate …

Intestinal epithelial cell (IEC) regulation of barrier function and mucosal homeostasis
enables the establishment of a harmonious gut microenvironment. However, host-derived …

Recruitment of neutrophils into and across the gut mucosa is a cardinal feature of intestinal
inflammation in response to enteric infections. Previous work using the model pathogen …

Summary Salmonella Typhimurium (S. Tm) utilizes the chemotaxis receptor Tsr to exploit gut
inflammation. However, the characteristics of this exploitation and the mechanism (s) …

Abstract JAK 2-V617F is the most frequent somatic mutation causing myeloproliferative
neoplasm (MPN). JAK2-V617F can be found in healthy individuals with clonal …

Postnatal establishment of enteric metabolic, host–microbial and immune homeostasis is the
result of precisely timed and tightly regulated developmental and adaptive processes. Here …