The continued threat of emerging flaviviruses

TC Pierson, MS Diamond - Nature microbiology, 2020 - nature.com
Flaviviruses are vector-borne RNA viruses that can emerge unexpectedly in human
populations and cause a spectrum of potentially severe diseases including hepatitis …

Tracking virus outbreaks in the twenty-first century

ND Grubaugh, JT Ladner, P Lemey, OG Pybus… - Nature …, 2019 - nature.com
Emerging viruses have the potential to impose substantial mortality, morbidity and economic
burdens on human populations. Tracking the spread of infectious diseases to assist in their …

Outbreak. info genomic reports: scalable and dynamic surveillance of SARS-CoV-2 variants and mutations

K Gangavarapu, AA Latif, JL Mullen, M Alkuzweny… - Nature …, 2023 - nature.com
In response to the emergence of SARS-CoV-2 variants of concern, the global scientific
community, through unprecedented effort, has sequenced and shared over 11 million …

Field-deployable viral diagnostics using CRISPR-Cas13

C Myhrvold, CA Freije, JS Gootenberg, OO Abudayyeh… - Science, 2018 - science.org
Mitigating global infectious disease requires diagnostic tools that are sensitive, specific, and
rapidly field deployable. In this study, we demonstrate that the Cas13-based SHERLOCK …

An amplicon-based sequencing framework for accurately measuring intrahost virus diversity using PrimalSeq and iVar

ND Grubaugh, K Gangavarapu, J Quick, NL Matteson… - Genome biology, 2019 - Springer
How viruses evolve within hosts can dictate infection outcomes; however, reconstructing this
process is challenging. We evaluate our multiplexed amplicon approach, PrimalSeq, to …

Multiplex PCR method for MinION and Illumina sequencing of Zika and other virus genomes directly from clinical samples

J Quick, ND Grubaugh, ST Pullan, IM Claro, AD Smith… - Nature protocols, 2017 - nature.com
Genome sequencing has become a powerful tool for studying emerging infectious diseases;
however, genome sequencing directly from clinical samples (ie, without isolation and …

Emerging role of non‐coding RNA in health and disease

GK Bhatti, N Khullar, IS Sidhu, US Navik… - Metabolic brain …, 2021 - Springer
Human diseases have always been a significant turf of concern since the origin of mankind.
It is cardinal to know the cause, treatment, and cure for every disease condition. With the …

Nanopore targeted sequencing for the accurate and comprehensive detection of SARS‐CoV‐2 and other respiratory viruses

M Wang, A Fu, B Hu, Y Tong, R Liu, Z Liu, J Gu… - Small, 2020 - Wiley Online Library
The ongoing global novel coronavirus pneumonia COVID‐19 outbreak has engendered
numerous cases of infection and death. COVID‐19 diagnosis relies upon nucleic acid …

Primary exposure to Zika virus is linked with increased risk of symptomatic dengue virus infection with serotypes 2, 3, and 4, but not 1

JV Zambrana, CM Hasund, RA Aogo, S Bos… - Science Translational …, 2024 - science.org
Infection with any of the four dengue virus serotypes (DENV1–4) can protect against or
enhance subsequent dengue depending on preexisting antibodies and infecting serotype …

The emergence of Zika virus and its new clinical syndromes

TC Pierson, MS Diamond - Nature, 2018 - nature.com
Zika virus (ZIKV) is a mosquito-transmitted flavivirus that has emerged as a global health
threat because of its potential to generate explosive epidemics and ability to cause …