[HTML][HTML] Reactive oxygen species in inflammation and tissue injury

SM Rizwan, P ReddySekhar… - Antioxidants & redox …, 2014 - liebertpub.com
Reactive oxygen species (ROS) are key signaling molecules that play an important role in
the progression of inflammatory disorders. An enhanced ROS generation by …

Structure, function, and regulation of the blood-brain barrier tight junction in central nervous system disorders

JJ Lochhead, J Yang, PT Ronaldson… - Frontiers in physiology, 2020 - frontiersin.org
The blood-brain barrier (BBB) allows the brain to selectively import nutrients and energy
critical to neuronal function while simultaneously excluding neurotoxic substances from the …

Redox control of microglial function: molecular mechanisms and functional significance

AI Rojo, G McBean, M Cindric, J Egea… - Antioxidants & redox …, 2014 - liebertpub.com
Neurodegenerative diseases are characterized by chronic microglial over-activation and
oxidative stress. It is now beginning to be recognized that reactive oxygen species (ROS) …

Vascular cell senescence contributes to blood–brain barrier breakdown

Y Yamazaki, DJ Baker, M Tachibana, CC Liu… - Stroke, 2016 - Am Heart Assoc
Background and Purpose—Age-related changes in the cerebrovasculature, including blood–
brain barrier (BBB) disruption, are emerging as potential risks for diverse neurological …

Blood-brain barrier disruption: a culprit of cognitive decline?

J Che, Y Sun, Y Deng, J Zhang - Fluids and Barriers of the CNS, 2024 - Springer
Cognitive decline covers a broad spectrum of disorders, not only resulting from brain
diseases but also from systemic diseases, which seriously influence the quality of life and …