Artificial cells: past, present and future

W Jiang, Z Wu, Z Gao, M Wan, M Zhou, C Mao… - ACS nano, 2022‏ - ACS Publications
Artificial cells are constructed to imitate natural cells and allow researchers to explore
biological process and the origin of life. The construction methods for artificial cells, through …

Liposomes and polymersomes: a comparative review towards cell mimicking

E Rideau, R Dimova, P Schwille, FR Wurm… - Chemical society …, 2018‏ - pubs.rsc.org
Cells are integral to all forms of life due to their compartmentalization by the plasma
membrane. However, living organisms are immensely complex. Thus there is a need for …

Microfluidic fabrication of microparticles for biomedical applications

W Li, L Zhang, X Ge, B Xu, W Zhang, L Qu… - Chemical Society …, 2018‏ - pubs.rsc.org
Droplet microfluidics offers exquisite control over the flows of multiple fluids in microscale,
enabling fabrication of advanced microparticles with precisely tunable structures and …

Advances in ultrahigh-throughput screening for directed enzyme evolution

U Markel, KD Essani, V Besirlioglu, J Schiffels… - Chemical Society …, 2020‏ - pubs.rsc.org
Enzymes are versatile catalysts and their synthetic potential has been recognized for a long
time. In order to exploit their full potential, enzymes often need to be re-engineered or …

Bioinspired polymer vesicles and membranes for biological and medical applications

CG Palivan, R Goers, A Najer, X Zhang, A Car… - Chemical society …, 2016‏ - pubs.rsc.org
Biological membranes play an essential role in living organisms by providing stable and
functional compartments, preserving cell architecture, whilst supporting signalling and …

[HTML][HTML] Mastering complexity: towards bottom-up construction of multifunctional eukaryotic synthetic cells

K Göpfrich, I Platzman, JP Spatz - Trends in biotechnology, 2018‏ - cell.com
With the ultimate aim to construct a living cell, bottom-up synthetic biology strives to
reconstitute cellular phenomena in vitro–disentangled from the complex environment of a …

H2O2-Responsive Vesicles Integrated with Transcutaneous Patches for Glucose-Mediated Insulin Delivery

X Hu, J Yu, C Qian, Y Lu, AR Kahkoska, Z **e, X **g… - ACS …, 2017‏ - ACS Publications
A self-regulated “smart” insulin administration system would be highly desirable for diabetes
management. Here, a glucose-responsive insulin delivery device, which integrates H2O2 …

Versatile phospholipid assemblies for functional synthetic cells and artificial tissues

X Wang, H Du, Z Wang, W Mu, X Han - Advanced materials, 2021‏ - Wiley Online Library
The bottom‐up construction of a synthetic cell from nonliving building blocks capable of
mimicking cellular properties and behaviors helps to understand the particular biophysical …

Polymersomes for therapeutic delivery of protein and nucleic acid macromolecules: from design to therapeutic applications

S Iqbal, M Blenner, A Alexander-Bryant… - …, 2020‏ - ACS Publications
Macromolecule-based therapeutic agents, particularly proteins, antigens, monoclonal
antibodies, transcription factors, nucleic acids, and gene editing enzymes, have the potential …

Core-shell microparticles: From rational engineering to diverse applications

X Zhang, Q Qu, A Zhou, Y Wang, J Zhang… - Advances in Colloid and …, 2022‏ - Elsevier
Core-shell microparticles, composed of solid, liquid, or gas bubbles surrounded by a
protective shell, are gaining considerable attention as intelligent and versatile carriers that …