Graphical abstract Abstract 7-Ketocholesterol (or 7-oxocholesterol) is an oxysterol
essentially formed by cholesterol autoxidation. It is often found at enhanced levels in the …

Abstract Background and Aims Lipid peroxidation end products are the major culprit for
inducing chronic diseases in elderly people. Along with the elevated level of lipid peroxide …

The one-electron reduction of lipid hydroperoxides by low-valent iron species is believed to
be a driver of cellular lipid peroxidation and associated ferroptotic cell death. We …

Aging is a complex biological process which can be associated with skeletal muscle
degradation leading to sarcopenia. The aim of this study consisted i) to determine the …

Cholesterol is an essential component of cell membranes and serves as an important
precursor of steroidal hormones and bile acids, but elevated levels of cholesterol and its …

Cholesterol is easily oxidized and can be transformed into numerous oxidation products,
among which oxysterols. Phytosterols are plant sterols related to cholesterol. Both oxysterols …

Cholesterol is a lipid of high nutritional value that easily undergoes oxidation through
enzymatic and non-enzymatic pathways, leading to a wide variety of cholesterol oxidation …

Oxidized cholesterols, the so-called oxysterols, are widely known to regulate cholesterol
homeostasis. However, more recently oxysterols have emerged as important lipid mediators …

Cholesterol oxidation products (COPs) are contaminants of food of animal origin. Increased
levels of these compounds in the human body are associated with an increased risk of many …

The impact of food processing on drug absorption, metabolism, and subsequent
pharmacological activity is a pressing yet insufficiently explored area of research …