Kaposi's sarcoma and its associated herpesvirus

EA Mesri, E Cesarman, C Boshoff - Nature Reviews Cancer, 2010 - nature.com
Kaposi's sarcoma (KS) is the most common cancer in HIV-infected untreated individuals.
Kaposi's sarcoma-associated herpesvirus (KSHV; also known as human herpesvirus 8 …

Herpes simplex virus 1 infection of neuronal and non-neuronal cells elicits specific innate immune responses and immune evasion mechanisms

AL Verzosa, LA McGeever, SJ Bhark… - Frontiers in …, 2021 - frontiersin.org
Alphaherpesviruses (α-HV) are a large family of double-stranded DNA viruses which cause
many human and animal diseases. There are three human α-HVs: Herpes Simplex Viruses …

[KNYGA][B] Pathology and genetics of tumours of soft tissue and bone

CDM Fletcher, KK Unni, F Mertens - 2002 - books.google.com
This WHO classification covers tumors of soft tissue and bone including inherited tumor
syndromes. Each entity is extensively discussed with information on clinicopathological …

KSHV and the pathogenesis of Kaposi sarcoma: listening to human biology and medicine

D Ganem - The Journal of clinical investigation, 2010 - jci.org
The linkage of Kaposi sarcoma (KS) to infection by a novel human herpesvirus (Kaposi
sarcoma–associated herpesvirus [KSHV]) is one of the great successes of contemporary …

Molecular genetics of Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) epidemiology and pathogenesis

LA Dourmishev, AL Dourmishev… - Microbiology and …, 2003 - journals.asm.org
Kaposi's sarcoma had been recognized as unique human cancer for a century before it
manifested as an AIDS-defining illness with a suspected infectious etiology. The discovery of …

Kaposi sarcoma: a continuing conundrum

RA Schwartz, G Micali, MR Nasca, L Scuderi - Journal of the American …, 2008 - Elsevier
Kaposi sarcoma (KS) remains a challenge. Its classic or Mediterranean form tends to be
benign. In transplant recipients it may be less so. As part of the AIDS pandemic, of which it …

KSHV infection and the pathogenesis of Kaposi's sarcoma

D Ganem - Annu. Rev. Pathol. Mech. Dis., 2006 - annualreviews.org
Kaposi's sarcoma (KS) has long been suspected of having an infectious etiology on the
basis of its unusual epidemiology, histopathology, and natural history. Nearly a decade ago …

Lytic KSHV infection inhibits host gene expression by accelerating global mRNA turnover

B Glaunsinger, D Ganem - Molecular cell, 2004 - cell.com
The stimulation of host gene expression by lytic gene products of Kaposi's sarcoma-
associated herpesvirus (KSHV) has been proposed to play a critical role in KS development …

Global metabolic profiling of infection by an oncogenic virus: KSHV induces and requires lipogenesis for survival of latent infection

T Delgado, EL Sanchez, R Camarda, M Lagunoff - 2012 - journals.plos.org
Like cancer cells, virally infected cells have dramatically altered metabolic requirements. We
analyzed global metabolic changes induced by latent infection with an oncogenic virus …

Immune deficiency and risk for malignancy among persons with AIDS

SM Mbulaiteye, RJ Biggar, JJ Goedert… - JAIDS Journal of …, 2003 - journals.lww.com
Background People with AIDS have an elevated risk for cancer. We studied the relationship
between cancer risk and AIDS-related immunosuppression as measured by CD4 count at …