Observed impairment in reciprocal social interaction is a diagnostic hallmark of autism
spectrum disorders. There is no effective medical treatment for these problems …

During pandemics, governments take drastic actions to prevent the spreading of the
disease, as seen during the present COVID-19 crisis. Sanctions of lockdown, social …

Background Overactivated microglia is involved in various kinds of neurodegenerative
diseases. Suppression of microglial overactivation has emerged as a novel strategy for …

Mother-infant contact has a critical role on brain development and behavior. Experiencing
early-life adversities (such as maternal separation stress or MS in rodents) results in …

Neuropeptide hormone oxytocin has roles in social bonding, energy metabolism, and
wound healing contributing to good physical, mental and social health. It was previously …

Traditionally associated with female reproduction, oxytocin (OT) was revisited recently and
was revealed to have several new roles in the cardiovascular system. Functional OT …

The hypothalamic neuroendocrine system is mainly composed of the neural structures
regulating hormone secretion from the pituitary gland and has been considered as the …

Oxytocin is synthesized and released in the heart and vasculature, tissues that also express
oxytocin receptors. Although it has been established this intrinsic cardiovascular oxytocin …

Enteric neurons express oxytocin (OT); moreover, enteric neurons and enterocytes express
developmentally regulated OT receptors (OTRs). Although OT (with secretin) opposes …

Oxytocin is a hormone and neurotransmitter found to have anti-inflammatory functions in
rodents. Here we used experimental bacterial endotoxinemia to examine the role of …