Chronic wasting disease of cervids: current knowledge and future perspectives

NJ Haley, EA Hoover - Annu. Rev. Anim. Biosci., 2015 - annualreviews.org
A naturally occurring transmissible spongiform encephalopathy (TSE) of mule deer was first
reported in Colorado and Wyoming in 1967 and has since spread to other members of the …

cerebral amyloid angiopathy, prion angiopathy, CADASIL and the spectrum of protein elimination failure angiopathies (PEFA) in neurodegenerative disease with a …

RO Carare, CA Hawkes, M Jeffrey… - Neuropathology and …, 2013 - Wiley Online Library
Failure of elimination of proteins from the brain is a major feature in many
neurodegenerative diseases. Insoluble proteins accumulate in brain parenchyma and in …

Animal prion diseases: the risks to human health

F Houston, O Andréoletti - Brain pathology, 2019 - Wiley Online Library
Transmissible spongiform encephalopathies (TSEs) or prion diseases of animals notably
include scrapie in small ruminants, chronic wasting disease (CWD) in cervids and classical …

An overview of animal prion diseases

M Imran, S Mahmood - Virology journal, 2011 - Springer
Prion diseases are transmissible neurodegenerative conditions affecting human and a wide
range of animal species. The pathogenesis of prion diseases is associated with the …

Prion strains: shining new light on old concepts

AJ Block, JC Bartz - Cell and Tissue Research, 2023 - Springer
Prion diseases are a group of inevitably fatal neurodegenerative disorders affecting
numerous mammalian species, including humans. The existence of heritable phenotypes of …

Evidence of scrapie transmission via milk

T Konold, SJ Moore, SJ Bellworthy… - BMC veterinary research, 2008 - Springer
Background The risk of scrapie infection increases with increased duration and proximity of
contact between sheep at lambing. Scrapie infectivity has not been detected in milk but …

Classical and atypical scrapie in sheep and goats. Review on the etiology, genetic factors, pathogenesis, diagnosis, and control measures of both diseases

C Acín, R Bolea, M Monzón, E Monleón, B Moreno… - Animals, 2021 - mdpi.com
Simple Summary Classical scrapie is a prionic, neurological, consumptive, and chronic
disease that affects naturally domestic small ruminants. It was initially described in the UK …

Emergence of CWD strains

A Otero, C Duque Velasquez, D McKenzie… - Cell and Tissue …, 2023 - Springer
Chronic wasting disease (CWD) strains present a novel challenge to defining and mitigating
this contagious prion disease of deer, elk, moose, and reindeer. Similar to strains of other …

Prion protein scrapie and the normal cellular prion protein

CJ Atkinson, K Zhang, AL Munn, A Wiegmans, MQ Wei - Prion, 2016 - Taylor & Francis
Prions are infectious proteins and over the past few decades, some prions have become
renowned for their causative role in several neurodegenerative diseases in animals and …

Conventional and state-of-the-art detection methods of bovine spongiform encephalopathy (BSE)

M Olech - International Journal of Molecular Sciences, 2023 - mdpi.com
Bovine spongiform encephalopathy (BSE) is a fatal neurodegenerative disease that belongs
to a group of diseases known as transmissible spongiform encephalopathies (TSEs). It is …