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A guide to the composition and functions of the extracellular matrix
Extracellular matrix (ECM) is a dynamic 3‐dimensional network of macromolecules that
provides structural support for the cells and tissues. Accumulated knowledge clearly …
provides structural support for the cells and tissues. Accumulated knowledge clearly …
The natural cytotoxicity receptors in health and disease
The Natural Cytotoxicity Receptors (NCRs), NKp46, NKp44, and NKp30, were some of the
first human activating Natural Killer (NK) cell receptors involved in the non-MHC-restricted …
first human activating Natural Killer (NK) cell receptors involved in the non-MHC-restricted …
Type I interferon autoantibodies are associated with systemic immune alterations in patients with COVID-19
Neutralizing autoantibodies against type I interferons (IFNs) have been found in some
patients with critical coronavirus disease 2019 (COVID-19), the disease caused by severe …
patients with critical coronavirus disease 2019 (COVID-19), the disease caused by severe …
The collagen family
S Ricard-Blum - Cold Spring Harbor perspectives in …, 2011 - cshperspectives.cshlp.org
Collagens are the most abundant proteins in mammals. The collagen family comprises 28
members that contain at least one triple-helical domain. Collagens are deposited in the …
members that contain at least one triple-helical domain. Collagens are deposited in the …
The role of extracellular matrix proteins in breast cancer
A Lepucki, K Orlińska, A Mielczarek-Palacz… - Journal of clinical …, 2022 - mdpi.com
The extracellular matrix is a structure composed of many molecules, including fibrillar (types
I, II, III, V, XI, XXIV, XXVII) and non-fibrillar collagens (mainly basement membrane collagens …
I, II, III, V, XI, XXIV, XXVII) and non-fibrillar collagens (mainly basement membrane collagens …
Collagen interactions: Drug design and delivery
Collagen is a major component in a wide range of drug delivery systems and biomaterial
applications. Its basic physical and structural properties, together with its low …
applications. Its basic physical and structural properties, together with its low …
Maximizing response to intratumoral immunotherapy in mice by tuning local retention
Direct injection of therapies into tumors has emerged as an administration route capable of
achieving high local drug exposure and strong anti-tumor response. A diverse array of …
achieving high local drug exposure and strong anti-tumor response. A diverse array of …
Transmembrane collagen receptors
B Leitinger - Annual review of cell and developmental biology, 2011 - annualreviews.org
Collagen, the most abundant protein in animals, is a key component of extracellular
matrices. Not only do collagens provide essential structural support for connective tissues …
matrices. Not only do collagens provide essential structural support for connective tissues …
A LAIR1 insertion generates broadly reactive antibodies against malaria variant antigens
Plasmodium falciparum antigens expressed on the surface of infected erythrocytes are
important targets of naturally acquired immunity against malaria, but their high number and …
important targets of naturally acquired immunity against malaria, but their high number and …
Biomaterial functionalization with triple-helical peptides for tissue engineering
JD Malcor, F Mallein-Gerin - Acta biomaterialia, 2022 - Elsevier
In the growing field of tissue engineering, providing cells in biomaterials with the adequate
biological cues represents an increasingly important challenge. Yet, biomaterials with …
biological cues represents an increasingly important challenge. Yet, biomaterials with …