A guide to the composition and functions of the extracellular matrix

NK Karamanos, AD Theocharis, Z Piperigkou… - The FEBS …, 2021 - Wiley Online Library
Extracellular matrix (ECM) is a dynamic 3‐dimensional network of macromolecules that
provides structural support for the cells and tissues. Accumulated knowledge clearly …

The natural cytotoxicity receptors in health and disease

AD Barrow, CJ Martin, M Colonna - Frontiers in immunology, 2019 - frontiersin.org
The Natural Cytotoxicity Receptors (NCRs), NKp46, NKp44, and NKp30, were some of the
first human activating Natural Killer (NK) cell receptors involved in the non-MHC-restricted …

Type I interferon autoantibodies are associated with systemic immune alterations in patients with COVID-19

MGP van der Wijst, SE Vazquez… - Science translational …, 2021 - science.org
Neutralizing autoantibodies against type I interferons (IFNs) have been found in some
patients with critical coronavirus disease 2019 (COVID-19), the disease caused by severe …

The collagen family

S Ricard-Blum - Cold Spring Harbor perspectives in …, 2011 - cshperspectives.cshlp.org
Collagens are the most abundant proteins in mammals. The collagen family comprises 28
members that contain at least one triple-helical domain. Collagens are deposited in the …

The role of extracellular matrix proteins in breast cancer

A Lepucki, K Orlińska, A Mielczarek-Palacz… - Journal of clinical …, 2022 - mdpi.com
The extracellular matrix is a structure composed of many molecules, including fibrillar (types
I, II, III, V, XI, XXIV, XXVII) and non-fibrillar collagens (mainly basement membrane collagens …

Collagen interactions: Drug design and delivery

B An, YS Lin, B Brodsky - Advanced drug delivery reviews, 2016 - Elsevier
Collagen is a major component in a wide range of drug delivery systems and biomaterial
applications. Its basic physical and structural properties, together with its low …

Maximizing response to intratumoral immunotherapy in mice by tuning local retention

N Momin, JR Palmeri, EA Lutz, N Jailkhani… - Nature …, 2022 - nature.com
Direct injection of therapies into tumors has emerged as an administration route capable of
achieving high local drug exposure and strong anti-tumor response. A diverse array of …

Transmembrane collagen receptors

B Leitinger - Annual review of cell and developmental biology, 2011 - annualreviews.org
Collagen, the most abundant protein in animals, is a key component of extracellular
matrices. Not only do collagens provide essential structural support for connective tissues …

A LAIR1 insertion generates broadly reactive antibodies against malaria variant antigens

J Tan, K Pieper, L Piccoli, A Abdi, M Foglierini… - Nature, 2016 - nature.com
Plasmodium falciparum antigens expressed on the surface of infected erythrocytes are
important targets of naturally acquired immunity against malaria, but their high number and …

Biomaterial functionalization with triple-helical peptides for tissue engineering

JD Malcor, F Mallein-Gerin - Acta biomaterialia, 2022 - Elsevier
In the growing field of tissue engineering, providing cells in biomaterials with the adequate
biological cues represents an increasingly important challenge. Yet, biomaterials with …