Shining new light on biological systems: luminescent transition metal complexes for bioimaging and biosensing applications

LCC Lee, KKW Lo - Chemical Reviews, 2024 - ACS Publications
Luminescence imaging is a powerful and versatile technique for investigating cell
physiology and pathology in living systems, making significant contributions to life science …

Molecularly engineered room-temperature phosphorescence for biomedical application: from the visible toward second near-infrared window

B Chang, J Chen, J Bao, T Sun, Z Cheng - Chemical Reviews, 2023 - ACS Publications
Phosphorescence, characterized by luminescent lifetimes significantly longer than that of
biological autofluorescence under ambient environment, is of great value for biomedical …

The development of anticancer ruthenium (II) complexes: from single molecule compounds to nanomaterials

L Zeng, P Gupta, Y Chen, E Wang, L Ji… - Chemical Society …, 2017 - pubs.rsc.org
Cancer is rapidly becoming the top killer in the world. Most of the FDA approved anticancer
drugs are organic molecules, while metallodrugs are very scarce. The advent of the first …

Cyclometalated iridium (III) complexes for life science

C Caporale, M Massi - Coordination Chemistry Reviews, 2018 - Elsevier
Photoluminescent cyclometalated iridium (III) complexes are now a well established class of
organometallic compounds with advantageous potential applications in biology and life …

Fluorescence microscopy—an outline of hardware, biological handling, and fluorophore considerations

SM Hickey, B Ung, C Bader, R Brooks, J Lazniewska… - Cells, 2021 - mdpi.com
Fluorescence microscopy has become a critical tool for researchers to understand biological
processes at the cellular level. Micrographs from fixed and live-cell imaging procedures …

Recent advances of iridium (III) metallophosphors for health-related applications

PY Ho, CL Ho, WY Wong - Coordination Chemistry Reviews, 2020 - Elsevier
Phosphorescent transition metal complexes have been intensively investigated, since these
luminophores are distinctively different from fluorescent chromophores in terms of the nature …

Cancer Cell‐Specific Fluorescent Prodrug Delivery Platforms

S Ma, JH Kim, W Chen, L Li, J Lee, J Xue… - Advanced …, 2023 - Wiley Online Library
Targeting cancer cells with high specificity is one of the most essential yet challenging goals
of tumor therapy. Because different surface receptors, transporters, and integrins are …

Real-time and high-fidelity tracking of lysosomal dynamics with a dicyanoisophorone-based fluorescent probe

J Hong, Q Li, Q **a, G Feng - Analytical Chemistry, 2021 - ACS Publications
The development of high-performance probes that can visualize and track the dynamic
changes of lysosomes is very important for the in-depth study of lysosomes. Herein, we …

Oncosis-inducing cyclometalated iridium (iii) complexes

R Guan, Y Chen, L Zeng, TW Rees, C **, J Huang… - Chemical …, 2018 - pubs.rsc.org
Oncosis is a non-apoptotic form of programmed cell death (PCD), which differs from
apoptosis in both morphological changes and inner pathways, and might hold the key to …

Discovery of an Ultra‐rapid and Sensitive Lysosomal Fluorescence Lipophagy Process

H Zhang, L Shi, K Li, X Liu, M Won… - Angewandte Chemie …, 2022 - Wiley Online Library
Non‐invasive dynamic tracking of lysosomes and their interactions with other organelles is
important for the study of lysosomal function and related diseases. However, many …