Single-cell transcriptomic approaches are revolutionizing neuroscience. Integrating this
wealth of data with morphology and physiology, for the comprehensive study of neuronal …

Astrocytes are ubiquitous within the central nervous system (CNS). These cells possess
many individual processes which extend out into the neuropil, where they interact with a …

Extended wakefulness is associated with reduced performance and the build-up of sleep
pressure. In the cortex, this manifests as changes in network activity. These changes show …

Retinal ganglion cells (RGCs) are the brain's gateway to the visual world. They can be
classified into different types on the basis of their electrophysiological, transcriptomic, or …

How the rich variety of neurons in the nervous system arises from neural stem cells is not
well understood. Using single-cell RNA-sequencing and in vivo confirmation, we uncover …

Understanding how neurons of the striatum are formed and integrate into complex synaptic
circuits is essential to provide insight into striatal function in health and disease. In this …

Since the beautiful images of Santiago Ramón y Cajal provided a first glimpse into the
immense diversity and complexity of cell types found in the cerebral cortex, neuroscience …

How to generate a brain of correct size and with appropriate cell-type diversity during
development is a major question in Neuroscience. In the develo** neocortex, radial glial …

Clones of excitatory neurons derived from a common progenitor have been proposed to
serve as elementary information processing modules in the neocortex. To characterize the …

I review recent technological advancements in coupling single-cell transcriptomics with
cellular phenotypes including morphology, calcium signaling, and electrophysiology. Single …