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Glioblastoma therapy: Past, present and future
E Obrador, P Moreno-Murciano… - International journal of …, 2024 - mdpi.com
Glioblastoma (GB) stands out as the most prevalent and lethal form of brain cancer.
Although great efforts have been made by clinicians and researchers, no significant …
Although great efforts have been made by clinicians and researchers, no significant …
Glioblastoma: current status, emerging targets, and recent advances
Glioblastoma (GBM) is a highly malignant brain tumor characterized by a heterogeneous
population of genetically unstable and highly infiltrative cells that are resistant to …
population of genetically unstable and highly infiltrative cells that are resistant to …
An overview of EGFR mechanisms and their implications in targeted therapies for glioblastoma
SMB Rodriguez, A Kamel, GV Ciubotaru… - International Journal of …, 2023 - mdpi.com
Despite all of the progress in understanding its molecular biology and pathogenesis,
glioblastoma (GBM) is one of the most aggressive types of cancers, and without an efficient …
glioblastoma (GBM) is one of the most aggressive types of cancers, and without an efficient …
Molecular markers in glioma
K Ludwig, HI Kornblum - Journal of neuro-oncology, 2017 - Springer
Gliomas are the most malignant and aggressive form of brain tumors, and account for the
majority of brain cancer related deaths. Malignant gliomas, including glioblastoma are …
majority of brain cancer related deaths. Malignant gliomas, including glioblastoma are …
The role of hypoxia in glioblastoma invasion
AR Monteiro, R Hill, GJ Pilkington, PA Madureira - Cells, 2017 - mdpi.com
Glioblastoma multiforme (GBM), a grade IV astrocytoma, is the most common and deadly
type of primary malignant brain tumor, with a patient's median survival rate ranging from 15 …
type of primary malignant brain tumor, with a patient's median survival rate ranging from 15 …
Updated insights on EGFR signaling pathways in glioma
A Oprita, SC Baloi, GA Staicu, O Alexandru… - International journal of …, 2021 - mdpi.com
Nowadays, due to recent advances in molecular biology, the pathogenesis of glioblastoma
is better understood. For the newly diagnosed, the current standard of care is represented by …
is better understood. For the newly diagnosed, the current standard of care is represented by …
Glioma stem cells and their roles within the hypoxic tumor microenvironment
Tumor microenvironments are the result of cellular alterations in cancer that support
unrestricted growth and proliferation and result in further modifications in cell behavior …
unrestricted growth and proliferation and result in further modifications in cell behavior …
Delivery of functional anti-miR-9 by mesenchymal stem cell–derived exosomes to glioblastoma multiforme cells conferred chemosensitivity
Glioblastoma multiforme (GBM), the most common and lethal tumor of the adult brain,
generally shows chemo-and radioresistance. MicroRNAs (miRs) regulate physiological …
generally shows chemo-and radioresistance. MicroRNAs (miRs) regulate physiological …
Challenges in glioblastoma immunotherapy: mechanisms of resistance and therapeutic approaches to overcome them
Glioblastoma is the most common and aggressive primary malignant brain tumour. The
prognosis of patients with glioblastoma is poor, and their overall survival averages at 1 year …
prognosis of patients with glioblastoma is poor, and their overall survival averages at 1 year …
Anticancer mechanism of curcumin on human glioblastoma
Glioblastoma (GBM) is the most malignant brain tumor and accounts for most adult brain
tumors. Current available treatment options for GBM are multimodal, which include surgical …
tumors. Current available treatment options for GBM are multimodal, which include surgical …