Cytokine storm is a general term applied to maladaptive cytokine release in response to
infection and other stimuli. The pathogenesis is complex but includes loss of regulatory …

Mesenchymal stem cells (MSCs) can be isolated from almost all tissues and effectively
expanded in vitro. Although their true in situ properties and biological functions remain to be …

Rationale: Mesenchymal stem/stromal cell (MSC) therapies have shown promise in
preclinical models of pathologies relevant to newborn medicine, such as bronchopulmonary …

Background No effective pharmacotherapy for acute respiratory distress syndrome (ARDS)
exists, and mortality remains high. Preclinical studies support the efficacy of mesenchymal …

Mesenchymal stem cells (MSC) are under investigation as a therapy for a variety of
disorders. Although animal models show long term regenerative and immunomodulatory …

Background—Hypoxia induces an inflammatory response in the lung manifested by
alternative activation of macrophages with elevation of proinflammatory mediators that are …

Mesenchymal stromal cells (MSC) have been reported to improve bacterial clearance in
preclinical models of Acute Respiratory Distress Syndrome (ARDS) and sepsis. The …

Various source-derived mesenchymal stem cells (MSCs) have been considered for cell
therapeutics in incurable diseases. To characterize MSCs from different sources, we …

We previously found that human mesenchymal stem cells (MSC) or its conditioned medium
restored lung protein permeability and reduced alveolar inflammation following Escherichia …

Abstract Background Mesenchymal stromal cells (MSCs) are attractive for cell-based
therapies ranging from regenerative medicine and tissue engineering to immunomodulation …