HFIP in organic synthesis

HF Motiwala, AM Armaly, JG Cacioppo… - Chemical …, 2022 - ACS Publications
1, 1, 1, 3, 3, 3-Hexafluoroisopropanol (HFIP) is a polar, strongly hydrogen bond-donating
solvent that has found numerous uses in organic synthesis due to its ability to stabilize ionic …

Transition-metal-catalyzed C–S, C–Se, and C–Te bond formations via cross-coupling and atom-economic addition reactions. Achievements and challenges

IP Beletskaya, VP Ananikov - Chemical Reviews, 2022 - ACS Publications
In the present review, we discuss recent progress in the field of C–Z bond formation
reactions (Z= S, Se, Te) catalyzed by transition metals. Two complementary methodologies …

Toolbox for distal C–H bond functionalizations in organic molecules

SK Sinha, S Guin, S Maiti, JP Biswas, S Porey… - Chemical …, 2021 - ACS Publications
Transition-metal-catalyzed C–H activation has developed a contemporary approach to the
omnipresent area of retrosynthetic disconnection. Scientific researchers have been tempted …

Synthesis and applications of sodium sulfinates (RSO 2 Na): a powerful building block for the synthesis of organosulfur compounds

RJ Reddy, AH Kumari - RSC advances, 2021 - pubs.rsc.org
This review highlights the preparation of sodium sulfinates (RSO2Na) and their multifaceted
synthetic applications. Substantial progress has been made over the last decade in the …

Recent advances in the catalytic synthesis of arylsulfonyl compounds

D Joseph, MA Idris, J Chen, S Lee - ACS Catalysis, 2021 - ACS Publications
Arylsulfonyl compounds are among the most important compounds in pharmaceutical and
medicinal chemistry. Hence, a wide variety of sulfonylation methods have been reported …

Radicals and Sulfur Dioxide: A Versatile Combination for the Construction of Sulfonyl‐Containing Molecules

K Hofman, NW Liu… - Chemistry–A European …, 2018 - Wiley Online Library
Molecules containing a sulfonyl functionality, such as sulfones, sulfonyl chlorides or
sulfonamides play an important role in organic chemistry and have found widespread …

Recent progress and emerging technologies towards a sustainable synthesis of sulfones

S Liang, K Hofman, M Friedrich, J Keller… - …, 2021 - Wiley Online Library
Sulfones play a pivotal role in modern organic chemistry. They are highly versatile building
blocks and find various applications as drugs, agrochemicals, or functional materials …

Recent advances in the sulfonylation of C–H bonds with the insertion of sulfur dioxide

G Qiu, K Zhou, J Wu - Chemical Communications, 2018 - pubs.rsc.org
Recent advances in the sulfonylation of C–H bonds with the insertion of sulfur dioxide are
summarized. Usually, a sulfur dioxide surrogate, DABCO·(SO2) 2, is used, which avoids the …

Chiral transient directing groups in transition-metal-catalyzed enantioselective C–H bond functionalization

MI Lapuh, S Mazeh, T Besset - ACS Catalysis, 2020 - ACS Publications
Transition-metal-catalyzed C–H bond functionalization has known a rapid evolution in the
last years, offering modern strategies for reaching high molecular complexity in a step-and …

Direct para-C–H heteroarylation of anilines with quinoxalinones by metal-free cross-dehydrogenative coupling under an aerobic atmosphere

J Xu, L Huang, L He, C Liang, Y Ouyang, J Shen… - Green …, 2021 - pubs.rsc.org
Herein, a green and efficient metal-free cross-dehydrogenative coupling (CDC) for the direct
para-C–H heteroarylation of anilines with quinoxalinones has been described. This reaction …