Ynamides are among the most powerful building blocks in organic synthesis and have
become invaluable starting materials for the construction of multifunctional compounds and …

Ynamides consist of a polarized triple bond that is directly attached to a nitrogen atom
carrying a sulfonyl, an alkoxycarbonyl, an acyl, or another electron withdrawing group. The …

A synthetic approach toward densely substituted enantiopure cyclic sulfinamides
possessing up to four consecutive stereogenic centers was developed based on a …

The highly enantioselective addition of terminal ynamides to a variety of isatins, catalyzed by
a bisoxazolidine copper complex under mild, base‐free reaction conditions, is described …

In this study, a novel strategy to access endocyclic sulfoximines in an enantiopure form is
reported. The approach is based on a silver nitrate‐catalyzed cyclo‐isomerization reaction …

Abstract An intramolecular [2+ 2] cycloaddition using N-sulfonyl substituted ynamides
tethered to an enone motif is described here. This thermally driven [2+ 2] cycloaddition …

The synthesis of pandamarilactonines in high enantiopurity is challenging due to the
configurational instability of the pyrrolidin-2-yl butenolide moiety present in these alkaloids …

Org. Synth. 2019, 96, 195-213 X DOI: 10.15227/orgsyn. 096.0195 196 character of the
nitrogen atom strongly polarizes the carbon–carbon triple bond, which can furnish …

Propargylamines are versatile compounds of great synthetic and therapeutic interest with
diverse ap-plications as versatile synthetic intermediates and as lead structures in drug …

Over the past 20 years, ynamides have clearly emerged as versatile building blocks in
organic synthesis allowing the construction of various nitrogen-containing molecules with …