Recent advances in 3d-block metal complexes with bi, tri, and tetradentate Schiff base ligands derived from salicylaldehyde and its derivatives: Synthesis …

M Kumar, AK Singh, AK Singh, RK Yadav… - Coordination Chemistry …, 2023 - Elsevier
Schiff bases have been of continued interest in coordination chemistry for a long time
because they provide new ligand platforms that make reactivity easier and their metal …

Copper complexes as antitumor agents: In vitro and in vivo evidence

LM Balsa, EJ Baran, IE León - Current medicinal chemistry, 2023 - ingentaconnect.com
Copper is an essential element for most aerobic organisms, with an important function as a
structural and catalytic cofactor, and in consequence, it is implicated in several biological …

Anticancer activity of a new copper (ii) complex with a hydrazone ligand. Structural and spectroscopic characterization, computational simulations and cell mechanistic …

LM Balsa, V Ferraresi-Curotto, MJ Lavecchia… - Dalton …, 2021 - pubs.rsc.org
We report here the synthesis, crystal structure, characterization and anticancer activity of a
copper (II)-hydrazone complex,[Cu (MeBHoVa)(H2O) 2](NO3)(for short, CuHL), against …

Anticancer and antimetastatic activity of copper (II)-tropolone complex against human breast cancer cells, breast multicellular spheroids and mammospheres

LM Balsa, MC Ruiz, LSM de la Parra, EJ Baran… - Journal of Inorganic …, 2020 - Elsevier
The goal of this work was to display the anticancer and antimetastatic activity of a copper (II)
with tropolone (trp), complex [Cu (trp) 2] toward human breast cancer cells in monolayer …

Promising Dual Anticancer and Antimetastatic Action by a Cu (II) Complex Derived from Acylhydrazone on Human Osteosarcoma Models

L Santa Maria de la Parra, AIB Romo… - Inorganic …, 2024 - ACS Publications
Osteosarcoma cancers are becoming more common in children and young adults, and
existing treatments have low efficacy and a very high mortality rate, making it pressing to …

DNA cleavage mechanism by metal complexes of Cu (II), Zn (II) and VO (IV) with a schiff-base ligand

MR Rodríguez, MJ Lavecchia, BS Parajón-Costa… - Biochimie, 2021 - Elsevier
Metal ions and metal complexes are important components of nucleic acid biochemistry,
participating both in regulation of gene expression and as therapeutic agents. Three new …

Zinc distribution within breast cancer tissue of different intrinsic subtypes

P Rusch, AV Hirner, O Schmitz, R Kimmig… - Archives of Gynecology …, 2021 - Springer
Purpose To show feasibility of laser ablation inductively coupled mass spectrometry (LA-
ICPMS) for analysis of zinc content and concentration in breast cancer tissue and to …

Recent developments in the biological activities of 3d-metal complexes with salicylaldehyde-based N, O-donor Schiff base ligands

M Kumar, AK Singh, VK Singh, RK Yadav… - Coordination Chemistry …, 2024 - Elsevier
Schiff base ligands have received attention due to their versatile coordination abilities and
potential applications in medicinal and biological fields. This investigation offers an in-depth …

Preparation, characterization, and computational study on transition metal complexes derived from thiophene Schiff base and evaluation of their cytotoxicity against …

FN Sayed, AM Ashmawy, GG Mohamed… - Applied …, 2024 - Wiley Online Library
Novel thiophene Schiff base ligand (L) was synthesized through the condensation of 2‐
thiophene‐methylamine and 3‐formyl‐4‐methoxyphenylboronic acid. Transition metal …

Copper (II) complexes as novel anticancer drug: Synthesis, spectral studies, crystal structures, in silico molecular docking and cytotoxicity

NA Mathews, MRP Kurup - Journal of Molecular Structure, 2022 - Elsevier
Three novel mixed ligand complexes of copper, derived from the parent
cyclohexylthiosemicarbazones were synthesized along with the secondary ligands such as …