Role of bioactive sphingolipids in physiology and pathology
A Gomez-Larrauri, N Presa… - Essays in …, 2020 - portlandpress.com
Sphingolipids are a class of complex lipids containing a backbone of sphingoid bases,
namely the organic aliphatic amino alcohol sphingosine (Sph), that are essential …
namely the organic aliphatic amino alcohol sphingosine (Sph), that are essential …
Pivotal role of paracrine effects in stem cell therapies in regenerative medicine: can we translate stem cell-secreted paracrine factors and microvesicles into better …
MZ Ratajczak, M Kucia, T Jadczyk, NJ Greco… - Leukemia, 2012 - nature.com
Although regenerative medicine is searching for pluripotent stem cells that could be
employed for therapy, various types of more differentiated adult stem and progenitor cells …
employed for therapy, various types of more differentiated adult stem and progenitor cells …
[HTML][HTML] G-CSF: From granulopoietic stimulant to bone marrow stem cell mobilizing agent
LJ Bendall, KF Bradstock - Cytokine & growth factor reviews, 2014 - Elsevier
G-CSF was among the first cytokines to be identified and rapidly transitioned into clinical
medicine. Initially used to promote the production of neutrophils in patients with …
medicine. Initially used to promote the production of neutrophils in patients with …
An update on sphingosine-1-phosphate and other sphingolipid mediators
H Fyrst, JD Saba - Nature chemical biology, 2010 - nature.com
Sphingolipids comprise a complex family of naturally occurring molecules that are enriched
in lipid rafts and contribute to their unique biochemical properties. Membrane sphingolipids …
in lipid rafts and contribute to their unique biochemical properties. Membrane sphingolipids …
Inhibiting the C5–C5a receptor axis
Activation of the complement system is a major pathogenic event that drives various
inflammatory responses in numerous diseases. All pathways of complement activation lead …
inflammatory responses in numerous diseases. All pathways of complement activation lead …
How I treat patients who mobilize hematopoietic stem cells poorly
Abstract Transplantation with 2-5× 106 mobilized CD34+ cells/kg body weight lowers
transplantation costs and mortality. Mobilization is most commonly performed with …
transplantation costs and mortality. Mobilization is most commonly performed with …
[HTML][HTML] Daily onset of light and darkness differentially controls hematopoietic stem cell differentiation and maintenance
Hematopoietic stem and progenitor cells (HSPCs) tightly couple maintenance of the bone
marrow (BM) reservoir, including undifferentiated long-term repopulating hematopoietic …
marrow (BM) reservoir, including undifferentiated long-term repopulating hematopoietic …
The great migration of bone marrow-derived stem cells toward the ischemic brain: therapeutic implications for stroke and other neurological disorders
CV Borlongan, LE Glover, N Tajiri, Y Kaneko… - Progress in …, 2011 - Elsevier
Accumulating laboratory studies have implicated the mobilization of bone marrow (BM)-
derived stem cells in brain plasticity and stroke therapy. This mobilization of bone cells to the …
derived stem cells in brain plasticity and stroke therapy. This mobilization of bone cells to the …
Mechanisms of G-CSF-mediated hematopoietic stem and progenitor mobilization
AM Greenbaum, DC Link - Leukemia, 2011 - nature.com
Under normal conditions, the great majority of hematopoietic stem/progenitors cells (HSPCs)
reside in the bone marrow. The number of HSPCs in the circulation can be markedly …
reside in the bone marrow. The number of HSPCs in the circulation can be markedly …
CD44, hyaluronan, the hematopoietic stem cell, and leukemia-initiating cells
M Zoeller - Frontiers in immunology, 2015 - frontiersin.org
CD44 is an adhesion molecule that varies in size due to glycosylation and insertion of so-
called variant exon products. The CD44 standard isoform (CD44s) is highly expressed in …
called variant exon products. The CD44 standard isoform (CD44s) is highly expressed in …