Membrane lipid homeostasis is a vital facet of bacterial cell physiology. For decades,
research in bacterial lipid synthesis was largely confined to the Escherichia coli model …

The idea of renewable and regenerative resources has inspired research for more than a
hundred years. Ideally, the only spent energy will replenish itself, like plant material …

Construction of living artificial cells from genes and molecules can expand our
understanding of life system and establish a new aspect of bioengineering. However, growth …

The ability to grow at moderate acidic conditions (pH 4.0–5.0) is important to Escherichia coli
colonization of the host's intestine. Several regulatory systems are known to control acid …

Lipid composition determines the physical properties of biological membranes and can vary
substantially between and within organisms. We describe a specific role for the viscosity of …

Plants, algae, and photosynthetic bacteria experience frequent changes in environment. The
ability to survive depends on their capacity to acclimate to such changes. In particular …

Fatty acids are primary metabolites synthesized by complex, elegant, and essential
biosynthetic machinery. Fatty acid synthases resemble an iterative assembly line, with an …

The bacterial domain produces numerous types of sphingolipids with various physiological
functions. In the human microbiome, commensal and pathogenic bacteria use these lipids to …

Gram-negative bacteria balance synthesis of the outer membrane (OM), cell wall, and
cytoplasmic contents during growth via unknown mechanisms. Here, we show that a …

FA (fatty acid) synthesis represents a central, conserved process by which acyl chains are
produced for utilization in a number of end-products such as biological membranes. Central …