Cytoplasmic dynein 1 is an important microtubule-based motor in many eukaryotic cells.
Dynein has critical roles both in interphase and during cell division. Here, we focus on …

Centrosome amplification is a hallmark of cancer. However, despite significant progress in
recent years, we are still far from understanding how centrosome amplification affects …

Microtubules and actin filaments are the two main cytoskeleton networks supporting
intracellular architecture and cell polarity. The centrosome nucleates and anchors …

Microtubules control cell architecture by serving as a scaffold for intracellular transport,
signaling, and organelle positioning. Microtubules are intrinsically polarized, and their …

Plasmodium falciparum is the causative agent of malaria and remains a pathogen of global
importance. Asexual blood stage replication, via a process called schizogony, is an …

Centrosomes are the microtubule-organizing centers of animal cells that organize
interphase microtubules and mitotic spindles. Centrioles are the microtubule-based …

In somatic cells, the position of the cell centroid is dictated by the centrosome. The
centrosome is instrumental in nucleus positioning, the two structures being physically …

Centrioles are eukaryotic subcellular structures that produce and regulate massive
cytoskeleton superstructures. They form centrosomes and cilia, regulate new centriole …

Epithelia form intelligent, dynamic barriers between the external environment and an
organism's interior. Intercellular cadherin-based adhesions adapt and respond to …

BACKGROUND: Cardiac ventricles provide the contractile force of the beating heart
throughout life. How the primitive endocardium-layered myocardial projections called …