Pathogenic microorganisms are causative agents of various infectious diseases that are
becoming increasingly serious worldwide. For the successful treatment of pathogenic …

The cysteine (Cys) proteome is a major component of the adaptive interface between the
genome and the exposome. The thiol moiety of Cys undergoes a range of biologic …

Biological copper is coordinated predominantly by just three ligand types: the side chains of
histidine, cysteine, and methionine, with of course some exceptions. The arrangement of …

Copper is well known for its antimicrobial and antiviral properties. Under aerobic conditions,
copper toxicity relies in part on the production of reactive oxygen species (ROS), especially …

Cu/Zn superoxide dismutase (SOD1) is a frontline antioxidant enzyme catalysing superoxide
breakdown and is important for most forms of eukaryotic life. The evolution of aerobic …

Metal transporters are a central component in the interaction of algae with their environment.
They represent the first line of defense to cellular perturbations in metal concentration, and …

Polysaccharide‐degrading mono‐copper lytic polysaccharide monooxygenases (LPMOs)
are efficient peroxygenases that require electron donors (reductants) to remain in the active …

Copper is a ubiquitous element in the environment as well as living organisms, with its redox
capabilities and complexation potential making it indispensable for many cellular functions …

Particulate methane monooxygenase (pMMO) is an integral membrane metalloenzyme that
oxidizes methane to methanol in methanotrophic bacteria, organisms that live on methane …

Metal ion assimilation is essential for all forms of life. However, organisms must properly
control the availability of these nutrients within the cell to avoid inactivating proteins by …