Determining the toxicity of chemicals is necessary to identify their harmful effects on humans,
animals, plants, or the environment. It is also one of the main steps in drug design. Animal …

Purpose: To present a review of most commonly used techniques to analyze dynamic
contrast‐enhanced magnetic resonance imaging (DCE‐MRI), discusses their strengths and …

Vascular endothelial growth factor (VEGF) pathway targeting agents have been combined
with other anticancer drugs, leading to improved efficacy in carcinoma of the cervix …

Advances in hardware and software have enabled the realization of clinically feasible,
quantitative multimodality imaging of tissue pathophysiology. Earlier efforts relating to …

Tracer-kinetic models allow for the quantification of kinetic parameters such as blood flow
from dynamic contrast-enhanced magnetic resonance (MR) images. Fitting the observed …

Delivery of anti-cancer drugs to tumor tissues, including their interstitial transport and cellular
uptake, is a complex process involving various biochemical, mechanical, and biophysical …

Tumors are often characterized by hypoxia, vascular abnormalities, low extracellular pH,
increased interstitial fluid pressure, altered choline-phospholipid metabolism, and aerobic …

Objective: To quantitatively evaluate blood–brain barrier changes in ischemic stroke patients
using dynamic contrast-enhanced (DCE) MRI. Methods: We examined 54 stroke patients …

Advances in X-ray computed tomography (CT) over the past 20 years have enabled non-
invasive imaging of the coronary arteries, as well as cardiac structure and function. Coronary …

Objective This study was undertaken to characterize the blood–brain barrier (BBB)
dysfunction in patients with new onset refractory status epilepticus (NORSE) using dynamic …