The physiology, pathology, and pharmacology of voltage-gated calcium channels and their future therapeutic potential
Voltage-gated calcium channels are required for many key functions in the body. In this
review, the different subtypes of voltage-gated calcium channels are described and their …
review, the different subtypes of voltage-gated calcium channels are described and their …
Structural biology and molecular pharmacology of voltage-gated ion channels
Voltage-gated ion channels (VGICs), including those for Na+, Ca2+ and K+, selectively
permeate ions across the cell membrane in response to changes in membrane potential …
permeate ions across the cell membrane in response to changes in membrane potential …
[HTML][HTML] Enterochromaffin cells are gut chemosensors that couple to sensory neural pathways
Dietary, microbial, and inflammatory factors modulate the gut-brain axis and influence
physiological processes ranging from metabolism to cognition. The gut epithelium is a …
physiological processes ranging from metabolism to cognition. The gut epithelium is a …
Voltage-gated calcium channels
WA Catterall - Cold Spring Harbor perspectives in …, 2011 - cshperspectives.cshlp.org
Voltage-gated calcium (Ca2+) channels are key transducers of membrane potential
changes into intracellular Ca2+ transients that initiate many physiological events. There are …
changes into intracellular Ca2+ transients that initiate many physiological events. There are …
An overview of the main genetic, epigenetic and environmental factors involved in autism spectrum disorder focusing on synaptic activity
E Masini, E Loi, AF Vega-Benedetti, M Carta… - International journal of …, 2020 - mdpi.com
Autism spectrum disorder (ASD) is a neurodevelopmental disorder that affects social
interaction and communication, with restricted interests, activity and behaviors. ASD is highly …
interaction and communication, with restricted interests, activity and behaviors. ASD is highly …
[HTML][HTML] Lymphatic vessel network structure and physiology
The lymphatic system is comprised of a network of vessels interrelated with lymphoid tissue,
which has the holistic function to maintain the local physiologic environment for every cell in …
which has the holistic function to maintain the local physiologic environment for every cell in …
Neuronal voltage-gated calcium channels: structure, function, and dysfunction
BA Simms, GW Zamponi - Neuron, 2014 - cell.com
Voltage-gated calcium channels are the primary mediators of depolarization-induced
calcium entry into neurons. There is great diversity of calcium channel subtypes due to …
calcium entry into neurons. There is great diversity of calcium channel subtypes due to …
Ion channels in cancer: are cancer hallmarks oncochannelopathies?
Genomic instability is a primary cause and fundamental feature of human cancer. However,
all cancer cell genotypes generally translate into several common pathophysiological …
all cancer cell genotypes generally translate into several common pathophysiological …
Vagal afferent innervation of the airways in health and disease
SB Mazzone, BJ Undem - Physiological reviews, 2016 - journals.physiology.org
Vagal sensory neurons constitute the major afferent supply to the airways and lungs.
Subsets of afferents are defined by their embryological origin, molecular profile …
Subsets of afferents are defined by their embryological origin, molecular profile …
Hypoxic pulmonary vasoconstriction
JT Sylvester, LA Shimoda, PI Aaronson… - Physiological …, 2012 - journals.physiology.org
It has been known for more than 60 years, and suspected for over 100, that alveolar hypoxia
causes pulmonary vasoconstriction by means of mechanisms local to the lung. For the last …
causes pulmonary vasoconstriction by means of mechanisms local to the lung. For the last …