[HTML][HTML] INSM1, a novel biomarker for detection of neuroendocrine neoplasms: cytopathologists' view

Z Maleki, A Nadella, M Nadella, G Patel, S Patel… - Diagnostics, 2021 - mdpi.com
Background: Insulinoma-associated protein 1 (INSM1) has been considered as a novel
immunostain for neuroendocrine tumors (NETs) and is hypothesized to be more reliable …

Neuroendocrine neoplasms of the breast: a review focused on the updated World Health Organization (WHO) morphologic classification

F Pareja, TM D'Alfonso - The Breast Journal, 2020 - Wiley Online Library
Neuroendocrine breast neoplasms are uncommon invasive carcinomas that have
historically been poorly defined due to various definitions of what constitutes a …

[HTML][HTML] Breast cancer with neuroendocrine differentiation: an update based on the latest WHO classification

JY Tsang, MT Gary - Modern Pathology, 2021 - Elsevier
Breast cancers with neuroendocrine (NE) differentiation are very heterogeneous, comprising
broadly cancers that are morphologically similar to NE tumors (NET) of other anatomic sites …

Expression of novel neuroendocrine markers in breast carcinomas: a study of INSM1, ASCL1, and POU2F3

E Zhong, F Pareja, MG Hanna, AA Jungbluth… - Human pathology, 2022 - Elsevier
Summary INSM1, ASCL1, and POU2F3 are novel transcription factors involved in
neuroendocrine (NE) differentiation of neoplasms in several organs, but data on their …

Rare histological variants of prostate adenocarcinoma: a national cancer database analysis

C Bronkema, S Arora, A Sood, D Dalela… - The Journal of …, 2020 - auajournals.org
Purpose: The American Joint Committee on Cancer recognizes 6 rare histological variants
of prostate adenocarcinoma. We describe the contemporary presentation and overall …

Insulinoma-associated protein 1 (INSM1): a potential biomarker and therapeutic target for neuroendocrine tumors

B Mahalakshmi, R Baskaran, M Shanmugavadivu… - Cellular Oncology, 2020 - Springer
Background Insulinoma-associated protein 1 (INSM1), a transcriptional regulator with a zinc-
finger DNA-binding domain, has been validated as a cytoplasmic marker for neuroendocrine …

INSM1 expression in breast neoplasms with neuroedocrine features

J Metovic, I Castellano, E Marinelli, S Osella-Abate… - Endocrine …, 2021 - Springer
According to the 2019 WHO classification of breast tumors, neuroendocrine neoplasms
(NENs) are classified into well-differentiated NE tumors (NET) and poorly differentiated NE …

[HTML][HTML] OTP, CD44, and Ki-67: A Prognostic Marker Panel for Relapse-Free Survival in Patients with Surgically Resected Pulmonary Carcinoid

L Moonen, JL Derks, MA den Bakker, LM Hillen… - Modern Pathology, 2025 - Elsevier
Although most patients with pulmonary carcinoid (PC) can be cured by surgery, relapse may
occur until 15 years after resection in up to 10% of patients. This is unpredictable at the …

[HTML][HTML] Orthopedia homeobox (OTP) in pulmonary neuroendocrine tumors: the diagnostic value and possible molecular interactions

L Moonen, J Derks, AM Dingemans, EJ Speel - Cancers, 2019 - mdpi.com
Generally, patients with stage I-IIIa (TNM) pulmonary carcinoid disease have a favourable
prognosis after curative resection. Yet, distant recurrence of disease after curative surgery …

Parathyroid neoplasms: immunohistochemical characterization and long noncoding RNA (lncRNA) expression

Q Yu, H Hardin, YH Chu, W Rehrauer, RV Lloyd - Endocrine Pathology, 2019 - Springer
Parathyroid adenomas are slow growing benign neoplasms associated with hypercalcemia,
while atypical parathyroid adenomas and parathyroid carcinomas are uncommon tumors …