Signaling pathways involved in ischemic stroke: molecular mechanisms and therapeutic interventions
C Qin, S Yang, YH Chu, H Zhang, XW Pang… - Signal transduction and …, 2022 - nature.com
Ischemic stroke is caused primarily by an interruption in cerebral blood flow, which induces
severe neural injuries, and is one of the leading causes of death and disability worldwide …
severe neural injuries, and is one of the leading causes of death and disability worldwide …
Macroautophagy in CNS health and disease
Macroautophagy is an evolutionarily conserved process that delivers diverse cellular
contents to lysosomes for degradation. As our understanding of this pathway grows, so does …
contents to lysosomes for degradation. As our understanding of this pathway grows, so does …
[HTML][HTML] The role and therapeutic potential of nuclear factor κB (NF-κB) in ischemic stroke
G Xu, F Dong, L Su, ZX Tan, M Lei, L Li, D Wen… - Biomedicine & …, 2024 - Elsevier
Stroke is a prevalent cerebrovascular condition with a global impact, causing significant
rates of illness and death. Despite extensive research, the available treatment options for …
rates of illness and death. Despite extensive research, the available treatment options for …
Advances of phytotherapy in ischemic stroke targeting PI3K/Akt signaling
T Liu, W Wang, X Li, Y Chen, F Mu, A Wen… - Phytotherapy …, 2023 - Wiley Online Library
The pathogenesis of ischemic stroke is complex, and PI3K/Akt signaling is considered to
play a crucial role in it. The PI3K/Akt pathway regulates inflammation, oxidative stress …
play a crucial role in it. The PI3K/Akt pathway regulates inflammation, oxidative stress …
The role of autophagy in idiopathic pulmonary fibrosis: from mechanisms to therapies
YL Yue, MY Zhang, JY Liu, LJ Fang… - … in Respiratory Disease, 2022 - journals.sagepub.com
Idiopathic pulmonary fibrosis (IPF) is an interstitial pulmonary disease with an extremely
poor prognosis. Autophagy is a fundamental intracellular process involved in maintaining …
poor prognosis. Autophagy is a fundamental intracellular process involved in maintaining …
Mechanisms underlying curcumin-induced neuroprotection in cerebral ischemia
F Fan, M Lei - Frontiers in pharmacology, 2022 - frontiersin.org
Ischemic stroke is the leading cause of death and disability worldwide, and restoring the
blood flow to ischemic brain tissues is currently the main therapeutic strategy. However …
blood flow to ischemic brain tissues is currently the main therapeutic strategy. However …
A new therapeutic trend: natural medicine for ameliorating ischemic stroke via PI3K/Akt signaling pathway
X Liu, X **ao, X Han, L Yao, W Lan - Molecules, 2022 - mdpi.com
Ischemic stroke (IS) is an acute cerebrovascular disease caused by sudden arterial
occlusion, which is characterized by a high morbidity, mortality, and disability rate. It is one of …
occlusion, which is characterized by a high morbidity, mortality, and disability rate. It is one of …
Pharmacological actions of myricetin in the nervous system: a comprehensive review of preclinical studies in animals and cell models
J Li, H **ang, C Huang, J Lu - Frontiers in Pharmacology, 2021 - frontiersin.org
Myricetin is a natural flavonoid extracted from a variety of plants, such as medicinal herbs,
vegetables, berries, and tea leaves. A growing body of evidence has reported that myricetin …
vegetables, berries, and tea leaves. A growing body of evidence has reported that myricetin …
Activin A alleviates neuronal injury through inhibiting cGAS-STING-mediated autophagy in mice with ischemic stroke
M Liu, Y Li, S Han, H Wang, J Li - Journal of Cerebral Blood …, 2023 - journals.sagepub.com
Activin A plays an essential role in ischemic stroke as a well-known neuroprotective factor.
We previously reported that Activin A could promote white matter remyelination. However …
We previously reported that Activin A could promote white matter remyelination. However …
mTOR pathway–a potential therapeutic target in stroke
K Melanis, MI Stefanou… - Therapeutic …, 2023 - journals.sagepub.com
Stroke is ranked as the second leading cause of death worldwide and a major cause of long-
term disability. A potential therapeutic target that could offer favorable outcomes in stroke is …
term disability. A potential therapeutic target that could offer favorable outcomes in stroke is …