Objectives To comprehensively review the existing studies of articaine in dentistry and
conduct a systematic review and meta-analysis to answer the following Population …

Over the past century, there is perhaps no greater contribution to the practice of clinical
dentistry than the development and application of local anaesthesia. What were once …

Local anesthetics are widely used during clinical cancer surgeries. Studies have suggested
that the use and the type of anesthesia affect cancer outcomes. In vivo studies and clinical …

Local anesthetics are frequently used by dentists to relieve localized discomfort of the
patient and improve treatment conditions. The risk of paresthesia after local anesthesia is …

The biochemical composition of articaine differs from other amide anaesthetics. The
lipophilic part of articaine consists of a thiophene ring, whereas other amide anaesthetics …

Bupivacaine (BUP) is an anesthetic commonly used in clinical practice that when used for
spinal anesthesia, might exert neurotoxic effects. Thioredoxin-interacting protein (TXNIP) is …

Local anaesthetics (LAs) may lead to neurological complications, but the underlying
mechanism is still unclear. Many neurotoxicity research studies have examined different …

The melanoma is responsible for the majority of all skin cancer–related deaths worldwide.
Evidence suggests that local anesthetics provide some benefit in the treatment of cancer via …

Administering local anesthetics (LAs) peri-and post-operatively aims to prevent or mitigate
pain in surgical procedures and after tissue injury in cases of osteoarthritis (OA) and other …

Injection of a variety of drugs such as local anesthetics (LAs) for peripheral nerve block has
been shown to cause damage to peripheral nerves. Bupivacaine is a local anesthetic widely …