Major strides have been made in the development of FLASH radiotherapy (FLASH RT) in
the last ten years, but there are still many obstacles to overcome for transfer to the clinic to …

FLASH radiotherapy is attracting increasing interest because it maintains tumor control while
inflicting less damage to normal tissues compared to conventional radiotherapy. This …

Objective. FLASH radiation therapy with ultrahigh dose rates (UHDR) has the potential to
reduce damage to normal tissue while maintaining anti-tumor efficacy. However, rapid and …

Objective. FLASH radiotherapy (FLASH-RT) with ultra-high dose rate (UHDR) irradiation
(ie> 40 Gy s− 1) spares the function of normal tissues while preserving antitumor efficacy …

Microfluidic chips exhibit unique advantages in both economy and rapidity, particularly for
the separation and detection of biomolecules. In this review, we first introduced the …

Dose rate is one of the important parameters in radiation-induced biomolecular damage.
The effects of dose rate have been known to modify radiation toxicity in biological systems …

Purpose The effects of conventional (CONV) and FLASH proton therapy on primary
bronchial epithelial cell (PBEC) organoids from individuals with chronic obstructive …

Background and purpose Understanding the cellular and molecular effect of proton
radiation, particularly the increased DNA damage complexity at the distal end of the Bragg …

We report the dose rate dependence of radiation chemical yields (G value) of water
radiolysis products under clinical energy protons (230 MeV) to understand mechanisms of …

The simulation of DNA damage and the subsequent biological response using Monte Carlo
simulation techniques is a pivotal area of research in radiation biology and biophysics …