TFOS DEWS II management and therapy report

L Jones, LE Downie, D Korb, JM Benitez-del-Castillo… - The ocular …, 2017 - Elsevier
The members of the Management and Therapy Subcommittee undertook an evidence-
based review of current dry eye therapies and management options. Management options …

Over the counter (OTC) artificial tear drops for dry eye syndrome

AD Pucker, SM Ng, JJ Nichols - Cochrane Database of …, 2016 - cochranelibrary.com
Background Over the counter (OTC) artificial tears historically have been the first line of
treatment for dry eye syndrome and dry eye‐related conditions like contact lens discomfort …

A comprehensive review on dry eye disease: diagnosis, medical management, recent developments, and future challenges

SP Phadatare, M Momin, P Nighojkar… - Advances in …, 2015 - Wiley Online Library
Dry eye syndrome (DES) or keratoconjunctivitis sicca (KCS) is a common disorder of the tear
film caused by decreased tear production or increased evaporation and manifests with a …

Predicted phenotypes of dry eye: proposed consequences of its natural history

AJ Bron, N Yokoi, E Gaffney, JM Tiffany - The ocular surface, 2009 - Elsevier
This paper reviews current knowledge of the pathophysiology of dry eye and predicts that
the clinical picture in late disease differs in both severity and quality from that in early …

A randomized, multicenter phase 3 study comparing 2% rebamipide (OPC-12759) with 0.1% sodium hyaluronate in the treatment of dry eye

S Kinoshita, K Oshiden, S Awamura, H Suzuki… - Ophthalmology, 2013 - Elsevier
OBJECTIVE: To investigate the efficacy of 2% rebamipide ophthalmic suspension compared
with 0.1% sodium hyaluronate ophthalmic solution for the treatment of patients with dry eye …

Rebamipide (OPC-12759) in the treatment of dry eye: a randomized, double-masked, multicenter, placebo-controlled phase II study

S Kinoshita, S Awamura, K Oshiden, N Nakamichi… - Ophthalmology, 2012 - Elsevier
OBJECTIVE: To investigate the dose response for efficacy of 1% and 2% rebamipide
ophthalmic suspension compared with placebo in patients with dry eye. DESIGN: A …

The association of vitamin D deficiency with tear break-up time and Schirmer testing in non-Sjögren dry eye

BE Kurtul, PA Özer, MS Aydinli - Eye, 2015 - nature.com
Purpose To investigate the effect of vitamin D deficiency on tear break-up time (TBUT) and
Schirmer test scores and to assess their relationship in non-Sjögren dry-eye patients …

Optimizing evaluation of Lissamine Green parameters for ocular surface staining

P Hamrah, F Alipour, S Jiang, JH Sohn, GN Foulks - Eye, 2011 - nature.com
Purpose The recently published seminal dry eye workshop proceedings defined Lissamine
Green (LG), an organic dye, as a gold standard for demonstrating ocular surface staining …

Treatment of dry eye syndrome with orally administered CF101: data from a phase 2 clinical trial

I Avni, HJ Garzozi, IS Barequet, F Segev, D Varssano… - Ophthalmology, 2010 - Elsevier
OBJECTIVE: To explore the safety and efficacy of CF101, an A3 adenosine receptor agonist,
in patients with moderate to severe dry eye syndrome. DESIGN: Phase 2, multicenter …

The effect of smoking on ocular surface and tear film based on clinical examination and optical coherence tomography

P Bhutia, S Sen, T Nath… - Indian Journal of …, 2021 - journals.lww.com
Purpose: Smoking is a global health problem with a high burden of smokers in India and the
world as well. Smoking is a known eye irritant that may have a significant effect on the …