Juvenile-onset systemic lupus erythematosus: update on clinical presentation, pathophysiology and treatment options

EMD Smith, H Lythgoe, A Midgley, MW Beresford… - Clinical …, 2019 - Elsevier
Juvenile-onset systemic lupus erythematosus (jSLE) accounts for up to 20% of all SLE
patients. Key differences between juvenile-and adult-onset (aSLE) disease include higher …

Lupus nephritis

S Wenderfer, S Mason, C Bernal, CAA da Silva - Pediatric Nephrology, 2022 - Springer
Childhood-onset systemic lupus erythematosus (cSLE) is a subset of SLE with onset prior to
16–18 years of age. Around 15% of patients with SLE present in childhood; patients with …

Association of rituximab use with adverse events in children, adolescents, and young adults

CL McAtee, J Lubega, K Underbrink, K Curry… - JAMA network …, 2021 - jamanetwork.com
Importance Rituximab is among the most frequently used immunotherapies in pediatrics.
Few studies have reported long-term adverse events associated with its use for children …

Towards development of treat to target (T2T) in childhood-onset systemic lupus erythematosus: PReS-endorsed overarching principles and points-to-consider from an …

EMD Smith, A Aggarwal, J Ainsworth, E Al-Abadi… - Annals of the rheumatic …, 2023 - Elsevier
Objectives Application of 'treat-to-target'(T2T) in childhood-onset systemic lupus
erythematosus (cSLE) may improve care and health outcomes. This initiative aimed to …

Rituximab treatment for chronic steroid-dependent Henoch-Schonlein purpura: 8 cases and a review of the literature

CB Crayne, E Eloseily, ML Mannion, SP Azerf… - Pediatric …, 2018 - Springer
Abstract Background Henoch-Schonlein purpura (HSP) is a small vessel vasculitis that is
characterized by non-thrombocytopenic purpura, abdominal pain, arthritis, and …

Belimumab for the treatment of pediatric patients with lupus nephritis

W Stohl, A Kwok - Expert Opinion on Biological Therapy, 2023 - Taylor & Francis
Introduction The FDA approved the anti-BAFF monoclonal antibody, belimumab, in 2011 for
adult systemic lupus erythematosus (SLE), in 2019 for pediatric SLE, in 2020 for adult lupus …

Advances in the care of children with lupus nephritis

SE Wenderfer, NM Ruth, HI Brunner - Pediatric research, 2017 - nature.com
The care of children with lupus nephritis (LN) has changed dramatically over the past 50 y.
The majority of patients with childhood-onset systemic lupus erythematosus (cSLE) develop …

Efficacy and safety of rituximab in the management of pediatric systemic lupus erythematosus: a systematic review

I Mahmoud, M Jellouli, I Boukhris, R Charfi… - The Journal of …, 2017 - Elsevier
Objectives To evaluate the efficacy and safety of rituximab for treating pediatric systemic
lupus erythematosus (pSLE). Study design We performed a systematic review to evaluate …

Differences in treatment of anti-NMDA receptor encephalitis: results of a worldwide survey

L Bartolini, E Muscal - Journal of neurology, 2017 - Springer
The objective of the study was to identify differences in treatment strategies for anti-NMDA
receptor encephalitis based on specialty of treating physicians, geographic location, and …

Current views on lupus in children

EMD Smith, H Lythgoe, CM Hedrich - Current Opinion in …, 2023 - journals.lww.com
Recent studies have significantly improved our understanding of jSLE pathogenesis,
highlighting important differences between jSLE and adult SLE, and providing the basis of …